We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Urinary retention and mydriasis secondary to topical glycopyrronium for axillary hyperhidrosis.
- Authors
Green, Holly Hoshall; Ray, Lance; Buchanan, Jennie; Matsler, Nikolaus
- Abstract
Purpose Glycopyrronium, also known as glycopyrrolate, is an antimuscarinic competitive inhibitor of acetylcholine widely utilized topically for its anticholinergic properties in dermatology. A single topical glycopyrronium tosylate (GT) formulation is available on the market, and prescription of this medication has become increasingly popular among dermatologists. This medication has a relatively notable adverse effect profile and carries risks that patients need to be counseled on before initiation. Summary A 22-year-old female presented to our emergency department (ED) with a chief complaint of difficulty urinating for 48 hours and blurred vision for 2 weeks. Over the course of a week, she visited the ED once and urgent care multiple times due to complications associated with combination use of GT and cetirizine. Although these clinical effects were reversible, the patient impact in our case was profound given the time, cost, and invasive nature of these visits. Conclusion The notable adverse effects of GT should be considered when prescribing this agent.
- Subjects
PARASYMPATHOMIMETIC agents; CETIRIZINE; AXILLA; GLYCOPYRROLATE; HYPERHIDROSIS; RETENTION of urine; VISION disorders; EYE diseases
- Publication
American Journal of Health-System Pharmacy, 2023, Vol 80, Issue 18, p1234
- ISSN
1079-2082
- Publication type
Article
- DOI
10.1093/ajhp/zxad141