We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Case report of oxalate nephropathy in a patient with pancreatic metastases from renal carcinoma.
- Authors
Purshouse, Karin; Chamberlain, Sarah; Soares, Maria; Tuthill, Mark; Protheroe, Andrew; Mole, David R.
- Abstract
<bold>Background: </bold>Patients with metastatic renal carcinoma frequently have pre-existing renal impairment and not infrequently develop worsening renal function as a complication of their treatment. The presence of pancreatic metastases in patients with metastatic renal carcinoma, often confers a more favourable prognosis and as a consequence this patient group may be exposed to such treatments for more prolonged periods of time. However, the development of renal failure may also be a consequence of the cancer itself rather than its treatment.<bold>Case Presentation: </bold>We present an 84-year-old patient receiving the tyrosine kinase inhibitor (TKI) pazopanib for metastatic renal carcinoma who developed oxalate nephropathy as a consequence of pancreatic exocrine insufficiency resulting from pancreatic metastases.<bold>Conclusions: </bold>This case demonstrates the importance of investigating unexpected toxicities and highlights the potential consequences of pancreatic insufficiency and its sequelae in patients with pancreatic metastases.
- Subjects
EXOCRINE pancreatic insufficiency; KIDNEY diseases; METASTASIS; PROTEIN-tyrosine kinases; CARCINOMA; KIDNEY failure
- Publication
BMC Cancer, 2019, Vol 19, Issue 1, pN.PAG
- ISSN
1471-2407
- Publication type
journal article
- DOI
10.1186/s12885-019-6215-y