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- Title
Cardiorespiratory Fitness Assessment for Exercise Research in Mild Cognitive Impairment Due to Alzheimer's Disease.
- Authors
Yu, Fang; Salisbury, Dereck; Lin, Feng Vankee
- Abstract
Purpose: To analyze cardiorespiratory fitness (CRF) levels using the gold-standard, laboratory-based cardiopulmonary exercise test (CPET) in community-dwelling older adults (N = 145) with amnestic mild cognitive impairment (aMCI), specifically CPET feasibility, CRF prediction, and CRF status in comparison to published sedentary, cognitively normal, age- and sex-adjusted normative data. Method: Peak oxygen consumption (VO2Peak [mL/kg/min]) was assessed by CPET, which was categorized as submaximal, near-maximal, or maximal tests. VO2Max predicted was compared to VO2Max measured to assess its utility. Data were analyzed with t tests. Results: Participants' mean age was 73.77 years (SD = 5.74 years), with 51.7% males, 91.7% Caucasian, 68.3% married, and 16.9 years (SD = 2.88 years) of education. Mean VO2Peak measured was 17.07 (SD = 4.92) for the total sample (18.29 [SD = 4.64] for males, 15.78 [SD = 4.91] for females). Sixteen (11.03%) CPETs were submaximal, 53 (36.55%) were near-maximal, and 76 (52.41%) were maximal. Mean VO2Max predicted was 28.59 (SD = 21.94) for the total sample (29.36 [SD = 22.3] for males, 27.76 [SD = 21.68] for females) and was significantly higher than VO2Max measured (p < 0.0001). Among participants with maximal CPETs, VO2Peak measured was significantly lower than sedentary normative data (p < 0.0001). Conclusion: CPET was feasible for older adults with aMCI. VO2Max predicted overly inflates CRF estimates. Low levels of CRF in older adults with aMCI suggest aerobic exercise as an important intervention. [Journal of Gerontological Nursing, 50(9), 31–36.]
- Subjects
CARDIOPULMONARY fitness; PREDICTIVE tests; ELDER care; REFERENCE values; ALZHEIMER'S disease; INDEPENDENT living; MILD cognitive impairment; COGNITIVE testing; ACADEMIC medical centers; SEDENTARY lifestyles; SEX distribution; QUESTIONNAIRES; DESCRIPTIVE statistics; CARDIOPULMONARY system; ELECTROCARDIOGRAPHY; COGNITION disorders; AEROBIC exercises; GERIATRIC Depression Scale; EXERCISE tests; OXYGEN consumption; DATA analysis software
- Publication
Journal of Gerontological Nursing, 2024, Vol 50, Issue 9, p31
- ISSN
0098-9134
- Publication type
Article
- DOI
10.3928/00989134-20240809-07