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- Title
Estimation of Extracellular Volume by a Two-Frequency Measurement.
- Authors
GOOVAERTS, H. G.; FAES, TH.J. C.; DE VALK-DE ROO, G. W.; TEN BOLSCHER, M.; NETELENBOSCH, J. C.; VAN DER VIJGH, W.J. F.; HEETHAAR, R. M.
- Abstract
A bstract: An approach to determine intra- and extracellular conduction on the basis of Bode analysis is presented. Estimation of the ratio between intra- and extracellular conduction could be performed by phase measurement only, midrange in the bandwidth of interest. An important feature is that the relation between intra- and extracellular conduction can be continuously monitored by phase measurement and no curve fitting whatsoever is required. Based on a two-frequency measurement determining Re at 4 kHz and ϕmax at 64 kHz, it proved possible to estimate extracellular volume (ECV) in 23 patients. Reference values on ECV were determined by sodium bromide. The results show a good correlation ( r= 0.90) with the reference method. The average error of ECV estimation was −3.6% (SD 8.4).
- Publication
Annals of the New York Academy of Sciences, 1999, Vol 873, Issue 1, p99
- ISSN
0077-8923
- Publication type
Article
- DOI
10.1111/j.1749-6632.1999.tb09455.x