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Results: 5000

EGR1 inhibits clear cell renal cell carcinoma proliferation and metastasis via the MAPK15 pathway.
Published in:
Oncology Research, 2025, v. 33, n. 2, p. 347, doi. 10.32604/or.2024.056039
By:
- PENG, NAIXIONG;
- CAI, YUEFENG;
- CHEN, DONG;
- DENG, LING;
- ZHANG, ZEJIAN;
- LI, WEI
Publication type:
Article
No free entry: stomatal state as decision maker in defining stress response strategies.
Published in:
Journal of Experimental Botany, 2025, v. 76, n. 2, p. 205, doi. 10.1093/jxb/erae447
By:
- Tarkowski, Łukasz P;
- Signorelli, Santiago
Publication type:
Article
Mitogen-activated protein kinase-mediated regulation of plant specialized metabolism.
Published in:
Journal of Experimental Botany, 2025, v. 76, n. 2, p. 262, doi. 10.1093/jxb/erae400
By:
- Zhou, Yan;
- Singh, Sanjay Kumar;
- Patra, Barunava;
- Liu, Yongliang;
- Pattanaik, Sitakanta;
- Yuan, Ling
Publication type:
Article
Targeting autophagy to enhance chemotherapy and immunotherapy in oral cancer.
Published in:
Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2024.1535649
By:
- Zeng, Xiaoli;
- Chen, Yue;
- Wang, Jing;
- He, Miao;
- Qiu, Junyao;
- Huang, Yun
Publication type:
Article
Synergetic role of TRPV4 inhibitor and mechanical loading on reducing inflammation.
Published in:
Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2024.1456042
By:
- Babaniamansour, Parto;
- Jacho, Diego;
- Rabino, Agustin;
- Garcia-Mata, Rafael;
- Yildirim-Ayan, Eda
Publication type:
Article
FGFR antagonists restore defective mandibular bone repair in a mouse model of osteochondrodysplasia.
Published in:
Bone Research, 2025, v. 13, n. 1, p. 1, doi. 10.1038/s41413-024-00385-x
By:
- Morice, Anne;
- de La Seiglière, Amélie;
- Kany, Alexia;
- Khonsari, Roman H.;
- Bensidhoum, Morad;
- Puig-Lombardi, Maria-Emilia;
- Legeai Mallet, Laurence
Publication type:
Article
Ultra-high Potency Topical Corticosteroids as a Potential Trigger for Reactive Perforating Collagenosis.
Published in:
Acta Dermato-Venereologica, 2024, v. 104, p. 1, doi. 10.2340/actadv.v104.40950
By:
- MADANCHI, Matiar;
- CURATOLO, Riccardo;
- JURATLI, Hazem A.;
- MANGAS, Cristina;
- MAINETTI, Carlo
Publication type:
Article
IL-7 secreted by keratinocytes induces melanogenesis via c-kit/MAPK signaling pathway in Melan-a melanocytes.
Published in:
Archives of Dermatological Research, 2025, v. 317, n. 1, p. 1, doi. 10.1007/s00403-024-03755-x
By:
- Lim, Ji Min;
- Sung, Hye Youn;
- Park, Seong Won;
- Hwang, Jae Sung
Publication type:
Article
Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties.
Published in:
Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1511627
By:
- Muslim, Wisam Taher;
- Mohammad, Layth Jasim;
- Naji, Munaf M.;
- Karimi, Isaac;
- Al-Sabti, Matheel D.;
- Jabir, Majid;
- Najm, Mazin A. A.;
- Schiöth, Helgi B.
Publication type:
Article
The role of tribbles homolog 2 in cell proliferation.
Published in:
Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-024-01985-0
By:
- Zhang, Wenkang;
- Li, Mingkang;
- Zhang, Minhao;
- Yan, Gaoliang;
- Tang, Chengchun
Publication type:
Article
Anti-leukemic effects of Vernonia amygdalina extract.
Published in:
Brazilian Journal of Biology, 2024, v. 84, p. 1, doi. 10.1590/1519-6984.287203
By:
- Hoang, T. C.;
- Nguyen, T. Q.;
- Bui, T. K. L.
Publication type:
Article
Activation of P38 MAPK Signaling Cascade is Linked with Clinical Outcomes and Therapeutic Responses in Human Cancers.
Published in:
Biochemistry (00062979), 2024, v. 89, n. 12, p. 2155, doi. 10.1134/S0006297924120058
By:
- Emelyanova, Aleksandra;
- Zolotovskaia, Marianna;
- Poddubskaya, Elena;
- Modestov, Aleksander;
- Buzdin, Anton;
- Kuzmin, Denis
Publication type:
Article
Hypomethylation of IL6ST promotes development of endometriosis by activating JAK2/STAT3 signaling pathway.
Published in:
PLoS ONE, 2025, v. 20, n. 1, p. 1, doi. 10.1371/journal.pone.0317569
By:
- Hu, Yue;
- Chen, Hailong;
- Jin, Lijuan;
- Chi, Xiumei;
- Zhao, Jian;
- Cao, Qinying
Publication type:
Article
The small GTPase MRAS is a broken switch.
Published in:
Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-55967-y
By:
- Bernal Astrain, Gabriela;
- Strakhova, Regina;
- Jo, Chang Hwa;
- Teszner, Emma;
- Killoran, Ryan C.;
- Smith, Matthew J.
Publication type:
Article
Radioiodine-refractory thyroid cancer—is it time to change the definition in light of novel redifferentiation therapies?
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2025, v. 52, n. 2, p. 380, doi. 10.1007/s00259-024-06991-5
By:
- Petranović Ovčariček, Petra;
- de Keizer, Bart;
- Campennì, Alfredo;
- Kreissl, Michael C.;
- Deandreis, Desiree;
- Tuncel, Murat;
- Giovanella, Luca
Publication type:
Article
Anti-allergic effect of 5,7-dihydroxy-4-methylcoumarin in IgE-mediated RBL-2H3 cells and PCA murine model.
Published in:
Applied Biological Chemistry, 2025, v. 68, n. 1, p. 1, doi. 10.1186/s13765-025-00980-4
By:
- Gwon, Sugeun;
- Shin, Seong-Ah;
- Kim, Moonsu;
- Moon, Sun Young;
- Choi, Seyeon;
- Kim, Minji;
- Lee, Jun Hyuck;
- Park, Hyun Ho;
- Lee, Chang Sup
Publication type:
Article
Exploring TNFR1: from discovery to targeted therapy development.
Published in:
Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06122-0
By:
- Li, Yingying;
- Ye, Ruiwei;
- Dai, Haorui;
- Lin, Jiayi;
- Cheng, Yue;
- Zhou, Yonghong;
- Lu, Yiming
Publication type:
Article
Study on the effect of massage on skeletal muscle overuse injury in rats based on MAPK signaling pathway.
Published in:
Journal of Beijing University of Traditional Chinese Medicine, 2024, v. 47, n. 12, p. 1, doi. 10.3969/j.issn.1006-2157.2024.12.017
By:
- Yimin, CHEN;
- Panpan, MU;
- Miaomiao, DUAN;
- Bo, HUANG;
- Law, RUAN;
- Liang, Peng
Publication type:
Article
Retinoic acid ameliorates rheumatoid arthritis by attenuating inflammation and modulating macrophage polarization through MKP-1/MAPK signaling pathway.
Published in:
Korean Journal of Physiology & Pharmacology, 2025, v. 29, n. 1, p. 45, doi. 10.4196/kjpp.24.079
By:
- Mengyuan Xin;
- Hangyu Jin;
- Xiangyu Guo;
- Liang Zhao;
- Xiangdan Li;
- Dongyuan Xu;
- Long Zheng;
- Lan Liu
Publication type:
Article
Computer-guided identification of novel inhibitors of apoptosis-signaling kinase 1 from Spondia mombim bioactive compounds against colorectal cancer.
Published in:
Egyptian Journal of Medical Human Genetics, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s43042-024-00625-z
By:
- Elekofehinti, Olusola Olalekan;
- Popoola, Hannah Oluwaseun;
- Oluwatuyi, Adedotun Olayemi;
- Iwaloye, Opeyemi;
- Akinjiyan, Moses Orimoloye;
- Cecilia, Oluwamodupe;
- Ogundolie, Frank Abimbola;
- Olatunde, Olalekan Isaac;
- Abchir, Oussama;
- Chtita, Samir;
- Rocha, Joao Batista Texeira
Publication type:
Article
A Narrative Review of the Role of Immunotherapy in Metastatic Carcinoma of the Colon Harboring a BRAF Mutation.
Published in:
In Vivo, 2025, v. 39, n. 1, p. 25, doi. 10.21873/invivo.13802
By:
- COLOMBO, ALFREDO;
- CONCETTA, PORRETTO MARIA;
- GEBBIA, VITTORIO;
- SAMBATARO, DANIELA;
- SCANDURRA, GIUSEPPINA;
- ROSARIA VALERIO, MARIA
Publication type:
Article
Osteoclastogenesis in Craniofacial Bone Defect: TNF-α and RANKL Interaction in Signaling Pathway at Guided Bone Regeneration as a Viable Treatment Option.
Published in:
Malaysian Journal of Medicine & Health Sciences, 2024, v. 20, p. 172, doi. 10.47836/mjmhs20.s12.24
By:
- Mahendra, Dedy Agoes;
- Yuliati, Anita;
- Razali, Masfueh Bt;
- Kasim, Noor Hayaty Bt Abu;
- Soesilawati, Pratiwi
Publication type:
Article
The SIRT5-JIP4 interaction promotes osteoclastogenesis by modulating RANKL-induced signaling transduction.
Published in:
Cell Communication & Signaling, 2025, p. 1, doi. 10.1186/s12964-024-02021-x
By:
- Zhu, Kecheng;
- Sheng, Chunxiang;
- Zhang, Linlin;
- Yang, Yuying;
- Chen, Xiaojing;
- Jiang, Tao;
- Song, Jiaxi;
- Zhang, Deng;
- Wang, Xiao;
- Zhao, Hongyan;
- Sun, Lihao;
- Zhou, Libin;
- Tao, Bei;
- Liu, Jianmin
Publication type:
Article
Non-small Cell Lung Cancer Cell Line PC-9 Drug-resistant Mutant Cell Line Establishment and Validation of Their Sensitivity to EGFR Inhibitors.
Published in:
Chinese Journal of Lung Cancer, 2024, v. 27, n. 11, p. 815, doi. 10.3779/j.issn.1009-3419.2024.101.31
By:
- Tao HU;
- Yang LOU;
- Mingbo SU
Publication type:
Article
Effect of atorvastatin on lipopolysaccharide-induced lung inflammation and hypoxia in mice; modulation of HIF-1α, CINC and MIP-2.
Published in:
Immunopharmacology & Immunotoxicology, 2025, v. 47, n. 1, p. 85, doi. 10.1080/08923973.2024.2436089
By:
- Salama, Abeer;
- El-Fadaly, Amany A.;
- Elgohary, Rania
Publication type:
Article
RUNX1 promotes proliferation of cervical cancer through TGFB2-MAPK pathway.
Published in:
Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-024-84254-x
By:
- Jia, Yongqin;
- Yang, Neng;
- Tang, Shuai;
- Deng, Li;
- Wang, Yanzhou;
- Cai, Xiongwei
Publication type:
Article
Differential effects of structurally different lysophosphatidylethanolamine species on proliferation and differentiation in pre-osteoblast MC3T3-E1 cells.
Published in:
Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-024-84176-8
By:
- Makiyama, Fumiaki;
- Kawase, Shiori;
- Omi, Aoi William;
- Tanikawa, Yusuke;
- Kotani, Taishi;
- Shirayama, Teruki;
- Nishimura, Naoyuki;
- Kurihara, Taiga;
- Saito, Naoto;
- Takahashi, Jun;
- Uemura, Takeshi
Publication type:
Article
A supercritical oil extract of Schisandra chinensis seeds ameliorates Huntington's disease-like symptoms and neuropathology: the potential role of anti-oxidant and anti-inflammatory effects.
Published in:
Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1471024
By:
- Jo, Hyo-Sung;
- Lee, Youn-Woo;
- Son, So-Ri;
- Jang, Dae Sik;
- Woo Kwon, Tae;
- Ha, Yujeong;
- Moon, Sang-Kwan;
- Kim, Min Soo;
- Cho, Ik-Hyun
Publication type:
Article
YAP/TEAD involvement in resistance to paclitaxel chemotherapy in lung cancer.
Published in:
Molecular & Cellular Biochemistry, 2025, v. 480, n. 1, p. 231, doi. 10.1007/s11010-024-04949-7
By:
- Brosseau, S.;
- Abreu, P.;
- Bouchez, C.;
- Charon, L.;
- Kieffer, Y.;
- Gentric, G.;
- Picant, V.;
- Veith, I.;
- Camonis, J.;
- Descroix, S.;
- Mechta-Grigoriou, F.;
- Parrini, M. C.;
- Zalcman, G.
Publication type:
Article
The role of MEK inhibition in pediatric low-grade gliomas.
Published in:
Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2024.1503894
By:
- Sheikh, Shehryar R.;
- Klesse, Laura J.;
- Mangum, Ross;
- Bui, Ashley;
- Siegel, Benjamin I.;
- Abdelbaki, Mohamed S.;
- Patel, Neha J.
Publication type:
Article
Deregulated JNK signaling enhances apoptosis during hyperthermia.
Published in:
International Journal of Hyperthermia, 2024, v. 41, n. 1, p. 1, doi. 10.1080/02656736.2024.2335199
By:
- Enomoto, Atsushi;
- Fukasawa, Takemichi;
- Terunuma, Hiroshi;
- Nakagawa, Keiichi;
- Yoshizaki, Ayumi;
- Sato, Shinichi;
- Hosoya, Noriko;
- Miyagawa, Kiyoshi
Publication type:
Article
Research Progress in Ulcerative Colitis: The Role of Traditional Chinese Medicine on Gut Microbiota and Signaling Pathways.
Published in:
American Journal of Chinese Medicine, 2024, v. 52, n. 8, p. 2277, doi. 10.1142/S0192415X24500885
By:
- Zhang, Yuyi;
- Zhu, Mingfang;
- Dai, Yueying;
- Gao, Longying;
- Cheng, Limin
Publication type:
Article
Anti-inflammatory Constituents Isolated From Launaea sarmentosa Against Infection by LPS-stimulated Macrophages.
Published in:
Records of Natural Products, 2024, v. 18, n. 6, p. 663, doi. 10.25135/rnp.487.2410.3343
By:
- Nguyen, Thanh Q. C.;
- Ta Thanh Hong;
- Vo Thanh Khang;
- Ho Thi Nhu Y.;
- Duy Toan Pham;
- Dang Huynh Giao;
- Truong Thi Tu Tran;
- Kaeko Kamei
Publication type:
Article
A monoamine oxidase B inhibitor altered gene expression of catalytically active dual-specificity phosphatases in human oral gingival keratinocytes.
Published in:
European Review for Medical & Pharmacological Sciences, 2024, v. 28, n. 24, p. 4681
By:
- OSTADKARAMPOUR, M.;
- PUTNINS, E. E.
Publication type:
Article
Augmentation of Deficient Bone Healing by Pulsed Electromagnetic Fields—From Mechanisms to Clinical Outcomes.
Published in:
Bioengineering (Basel), 2024, v. 11, n. 12, p. 1223, doi. 10.3390/bioengineering11121223
By:
- Kaadan, Amr;
- Salati, Simona;
- Setti, Stefania;
- Aaron, Roy
Publication type:
Article
Network pharmacology and molecular docking to explore mechanisms of clozapine-induced cardiac arrest.
Published in:
Journal of Psychiatry & Neuroscience, 2025, v. 50, n. 1, p. E1, doi. 10.1503/jpn.240065
By:
- Chen, Ximing;
- Zhuo, Chuanjun;
- Yang, Lei;
- Zhang, Qiuyu;
- Chao, Li
Publication type:
Article
Differential TLR-ERK1/2 Activity Promotes Viral ssRNA and dsRNA Mimic-Induced Dysregulated Immunity in Macrophages.
Published in:
Pathogens, 2024, v. 13, n. 12, p. 1033, doi. 10.3390/pathogens13121033
By:
- Shrestha, Rakshya;
- Johnson, Paige Marie;
- Ghimire, Roshan;
- Whitley, Cody John;
- Channappanavar, Rudragouda
Publication type:
Article
Extracellular Vesicles from Plasma of Patients with Glioblastoma Promote Invasion of Glioblastoma Cells Even After Tumor Resection.
Published in:
Biomedicines, 2024, v. 12, n. 12, p. 2834, doi. 10.3390/biomedicines12122834
By:
- Lyukmanova, Ekaterina N.;
- Kirichenko, Artem V.;
- Medyanik, Igor A.;
- Yashin, Konstantin S.;
- Kirpichnikov, Mikhail P.;
- Bychkov, Maxim L.
Publication type:
Article
Vanillin Has Potent Antibacterial, Antioxidant, and Anti-Inflammatory Activities In Vitro and in Mouse Colitis Induced by Multidrug-Resistant Escherichia coli.
Published in:
Antioxidants, 2024, v. 13, n. 12, p. 1544, doi. 10.3390/antiox13121544
By:
- Wang, Jiaxue;
- An, Wei;
- Wang, Zhenlong;
- Zhao, Ya;
- Han, Bing;
- Tao, Hui;
- Wang, Jinquan;
- Wang, Xiumin
Publication type:
Article
Thiol-Based Redox Molecules: Potential Antidotes for Acrylamide Toxicity.
Published in:
Antioxidants, 2024, v. 13, n. 12, p. 1431, doi. 10.3390/antiox13121431
By:
- Martin, Valeria;
- Trus, Michael;
- Atlas, Daphne
Publication type:
Article
The ‌BCL2-associated athanogene-3–Interferon-induced transmembrane protein 2 axis enhances pancreatic ductal adenocarcinoma growth via the Mitogen-activated protein kinase signaling pathway.
Published in:
Carcinogenesis, 2024, v. 45, n. 12, p. 928, doi. 10.1093/carcin/bgae053
By:
- Wang, Peipei;
- Chen, Congliang;
- Lin, Kexin;
- Zhang, Yu;
- Hu, Junmei;
- Zhu, Tongbo;
- Wang, Xia
Publication type:
Article
Expression levels of some genes in the MAPK pathway (DUSP1, DUSP2, DUSP4, DUSP6 and DUSP10) in eyelid tumor tissue.
Published in:
Turkish Journal of Biochemistry / Turk Biyokimya Dergisi, 2024, v. 49, n. 6, p. 757, doi. 10.1515/tjb-2023-0279
By:
- Ozmen, Esma;
- Tas, Ayca;
- Akin, Dilara Fatma;
- Erdogan, Haydar;
- Silig, Yavuz
Publication type:
Article
YWHAG promotes bladder cancer metastasis by regulating TMOD3 to activate ERK1/2 and JNK phosphorylation in the MAPK pathway.
Published in:
Journal of Translational Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12967-024-06003-y
By:
- Tian, Tai;
- He, Shiming;
- Hao, Han;
- Guan, Bao;
- Gong, Yanqing;
- Fan, Jian;
- Zhu, Zhenpeng;
- Gao, Wenzhi;
- Wu, Yucai;
- Feng, Ninghan;
- Wang, Aixiang;
- Guo, Yuexian;
- Li, Xuesong
Publication type:
Article
Exploring the In Vitro Effects of Zingerone on Differentiation and Signalling Pathways in Bone Cell Lines.
Published in:
Metabolites (2218-1989), 2024, v. 14, n. 12, p. 693, doi. 10.3390/metabo14120693
By:
- De Vos, Brunhildé;
- Kasonga, Abe E.;
- Joubert, Anna M.;
- Nyakudya, Trevor T.
Publication type:
Article
Novel Antimicrobial and Antitumor Agents Bearing Pyridine-1,2,4-triazole-3-thione-hydrazone Scaffold: Synthesis, Biological Evaluation, and Molecular Docking Investigation.
Published in:
Biomolecules (2218-273X), 2024, v. 14, n. 12, p. 1529, doi. 10.3390/biom14121529
By:
- Šermukšnytė, Aida;
- Stasevych, Maryna;
- Komarovska-Porokhnyavets, Olena;
- Zvarych, Viktor;
- Jakubauskienė, Eglė;
- Kantminienė, Kristina;
- Tumosienė, Ingrida
Publication type:
Article
Visfatin Enhances RANKL-Induced Osteoclastogenesis In Vitro: Synergistic Interactions and Its Role as a Mediator in Osteoclast Differentiation and Activation.
Published in:
Biomolecules (2218-273X), 2024, v. 14, n. 12, p. 1500, doi. 10.3390/biom14121500
By:
- Ok, Chang Youp;
- Kwon, Ryuk Jun;
- Jang, Hye-Ock;
- Bae, Moon-Kyoung;
- Bae, Soo-Kyung
Publication type:
Article
Anti-Allergic Effects of Lonicera caerulea L. Extract and Cyanidin-3-Glucoside on Degranulation and FcεRI Signaling Pathway of RBL-2H3 Cells.
Published in:
Applied Sciences (2076-3417), 2024, v. 14, n. 24, p. 11722, doi. 10.3390/app142411722
By:
- Choi, Ye-Eun;
- Yang, Jung-Mo;
- Jeong, Chae-Won;
- Park, Sung-Hwan;
- Yoo, Hee-Won;
- Jo, Hyun-Duck;
- Cho, Ju-Hyun
Publication type:
Article
Recruitment of neutrophils in glomeruli in early mouse sepsis is associated with E-selectin expression and activation of endothelial nuclear factor kappa-light-chain-enhancer of activated B cells and mitogen-activated protein kinase pathways.
Published in:
Journal of Leukocyte Biology, 2024, v. 116, n. 6, p. 1479, doi. 10.1093/jleuko/qiae146
By:
- Wang, Zhendong;
- Dayang, Erna-Zulaikha;
- Zwiers, Peter J;
- Garcia, Martha L Hernandez;
- Luxen, Matthijs;
- Meurs, Matijs van;
- Kamps, Jan A A M;
- Moser, Jill;
- Molema, Grietje
Publication type:
Article
Speak, friend, and enter: signalling systems that promote beneficial symbiotic associations in plants.
Published in:
Nature Reviews Microbiology, 2013, v. 11, n. 4, p. 252, doi. 10.1038/nrmicro2990
By:
- Oldroyd, Giles E. D.
Publication type:
Article
An epigenetic effector.
Published in:
Nature Reviews Microbiology, 2007, v. 5, n. 2, p. 87, doi. 10.1038/nrmicro1606
By:
- Molloy, Sheilagh
Publication type:
Article