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- Title
Acid cyclization of amino-substituted heterocycles. Synthesis of 1,3-dioxo- pyrrolo[3,4- c]- and thieno[3,4- c]isoquino- lines and cinnolines.
- Authors
Zinchenko, S. Yu.; Efimenko, R. A.; Suikov, S. Yu.; Kobrakov, K. I.; Bogza, S. L.
- Abstract
The reaction of 3-amino-4-(3,4-dimethoxyphenyl)maleimide and the methyl esters of 3-amino-4-(3,4-dimethoxyphenyl)-5-R-thiophene-2-carboxylic acids with carbonyl compounds and nitrous acid has been investigated. Dioxopyrrolo[3,4- c]- and thieno[3,4- c]isoquinolines and cinnolines were obtained.
- Subjects
QUINOLINE; RING formation (Chemistry); HETEROCYCLIC compounds; ACIDS; CARBOXYLIC acids; NITROUS acid; THIOPHENES
- Publication
Chemistry of Heterocyclic Compounds, 2009, Vol 45, Issue 3, p365
- ISSN
0009-3122
- Publication type
Article
- DOI
10.1007/s10593-009-0262-2