We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Influence of epigallocatechin gallate on methylxanthines-induced diuresis in rats.
- Authors
Manami Monobe; Sachiko Nomura; Akiko Ogino
- Abstract
Green tea leaves of Camellia sinensis L. contain 2-4% (dry weight: DW) caffeine, whereas Camellia ptilophylla Chang, called cocoa tea, contains about 4% (DW) theobromine instead of caffeine. Methylxanthines such as caffeine, theobromine, and theophylline are generally known to induce a diuresis. Recently, several reports have suggested that epigallocatechin gallate (EGCG) may influence the effects of caffeine. The above-mentioned Camellia contain up to about 10% (DW) of EGCG in addition to caffeine or theobromine. Therefore, in this study, we evaluated whether the diuretic activity in rats induced by oral administration of caffeine and theobromine (5 mg/kg body weight: b.w.) was affected by the coexistence of EGCG (10 mg/kg b.w.).
- Subjects
EPIGALLOCATECHIN gallate; METHYLXANTHINES; DIURESIS; ORAL drug administration; TEA; GREEN tea; RATS
- Publication
Japanese Journal of Food Chemistry & Safety, 2023, Vol 30, Issue 1, p29
- ISSN
1341-2094
- Publication type
Article