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- Title
Contact allergy to bufexamac.
- Authors
Perret, Christian M.; Happle, Rudolf
- Abstract
Bufexamac is an NSAID used for topical treatment of the skin and mucous membranes. It belongs to the arylacanoic acid family, as do naproxol and diclofenac. Its sensitizing potential seems to be low. In the Magnusson & Kligman maximization test, contact sensitization could not be induced. Clinically, adverse reactions are also rare. In 5 additional cases studied, sensitization became apparent after periods of treatment from 2 to 10 months. No contact sensitization to other ingredients of bufexamac preparations was detected. In patients with exacerbations of long-standing eczemas, contact allergy to bufexamac should be considered.
- Subjects
NONSTEROIDAL anti-inflammatory agents; ALLERGIES; MUCOUS membranes; ANTISEPTICS; ECZEMA; SKIN inflammation
- Publication
Contact Dermatitis (01051873), 1989, Vol 20, Issue 4, p307
- ISSN
0105-1873
- Publication type
Article
- DOI
10.1111/j.1600-0536.1989.tb03154.x