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- Title
Improved Visual Outcome and Low Recurrence with Early Treatment with Intravitreal Anti-Vascular Endothelial Growth Factor in Myopic Choroidal Neovascularization.
- Authors
Moon, Byung Gil; Cho, ah Ran; Lee, Junyeop; Kim, Yoon Jeon; Lee, Joo Yong; Kim, June-Gone; Yoon, Young Hee
- Abstract
Purpose: The aim of this study was to determine the correlation between the duration of myopic choroidal neovascularization (CNV) and treatment outcome after anti-vascular endothelial growth factor (VEGF) injections. Methods: We performed a retrospective review of treatment-naïve myopic CNV patients who were treated with anti-VEGF and followed for at least 24 months to identify factors predicting final outcome and recurrence. Results: Among 106 eyes, a shorter duration of CNV was a significant predictor of a better final bestcorrected visual acuity, even after controlling for other factors (p = 0.042). When divided into 3 groups according to CNV duration before treatment (<2, 2-8, and 8-24 weeks), the recurrence rate (19, 25, and 52%, respectively; p = 0.006) and number of injections (3.5, 4.0, and 5.5, respectively; p = 0.021) were significantly lower in eyes with a shorter duration of CNV. Conclusions: Early anti-VEGF treatment of myopic CNV decreased the recurrence rate and number of injections and improved visual outcome.
- Subjects
NEOVASCULARIZATION; VASCULAR endothelial growth factors; VISUAL acuity; BLOOD-vessel development; PATHOLOGIC neovascularization
- Publication
Ophthalmologica, 2017, Vol 237, Issue 3, p128
- ISSN
0030-3755
- Publication type
Article
- DOI
10.1159/000458160