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Spatial resolution of the head and neck cancer tumor microenvironment to identify tumor and stromal features associated with therapy response.
Published in:
Immunology & Cell Biology, 2024, v. 102, n. 9, p. 830, doi. 10.1111/imcb.12811
By:
- Berrell, Naomi;
- Monkman, James;
- Donovan, Meg;
- Blick, Tony;
- O'Byrne, Ken;
- Ladwa, Rahul;
- Tan, Chin Wee;
- Kulasinghe, Arutha
Publication type:
Article
Spatial proteomics identifies a spectrum of immune dysregulation in acquired bone marrow failure syndromes.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1213560
By:
- Koldej, Rachel M.;
- Prabahran, Ashvind;
- Chin Wee Tan;
- Ludford-Menting, Mandy;
- Morgan, Huw;
- Holzwart, Nicholas;
- Davis, Melissa J.;
- Ritchie, David S.
Publication type:
Article
Compartmentalized spatial profiling of the tumor microenvironment in head and neck squamous cell carcinoma identifies immune checkpoint molecules and tumor necrosis factor receptor superfamily members as biomarkers of response to immunotherapy.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1135489
By:
- Sadeghirad, Habib;
- Ning Liu;
- Monkman, James;
- Ma, Ning;
- Cheikh, Bassem Ben;
- Jhaveri, Niyati;
- Tan, Chin Wee;
- Warkiani, Majid Ebrahimi;
- Adams, Mark N.;
- Quan Nguyen;
- Ladwa, Rahul;
- Braubach, Oliver;
- O'Byrne, Ken;
- Davis, Melissa;
- Hughes, Brett G. M.;
- Kulasinghe, Arutha
Publication type:
Article
Compartmentalized spatial profiling of the tumor microenvironment in head and neck squamous cell carcinoma identifies immune checkpoint molecules and tumor necrosis factor receptor superfamily members as biomarkers of response to immunotherapy.
Published in:
Frontiers in Immunology, 2023, v. 14, p. 01, doi. 10.3389/fimmu.2023.1135489
By:
- Sadeghirad, Habib;
- Ning Liu;
- Monkman, James;
- Ning Ma;
- Cheikh, Bassem Ben;
- Jhaveri, Niyati;
- Chin Wee Tan;
- Warkiani, Majid Ebrahimi;
- Adams, Mark N.;
- Quan Nguyen;
- Ladwa, Rahul;
- Braubach, Oliver;
- O'Byrne, Ken;
- Davis, Melissa;
- Hughes, Brett G. M.;
- Kulasinghe, Arutha
Publication type:
Article
Modelling the effect of subcellular mutations on the migration of cells in the colorectal crypt.
Published in:
BMC Bioinformatics, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s12859-020-3391-3
By:
- Romijn, Lotte B.;
- Almet, Axel A.;
- Tan, Chin Wee;
- Osborne, James M.
Publication type:
Article
standR: spatial transcriptomic analysis for GeoMx DSP data.
Published in:
Nucleic Acids Research, 2024, v. 52, n. 1, p. e2, doi. 10.1093/nar/gkad1026
By:
- Liu, Ning;
- Bhuva, Dharmesh D;
- Mohamed, Ahmed;
- Bokelund, Micah;
- Kulasinghe, Arutha;
- Tan, Chin Wee;
- Davis, Melissa J
Publication type:
Article
vissE.cloud: a webserver to visualise higher order molecular phenotypes from enrichment analysis.
Published in:
Nucleic Acids Research, 2023, v. 51, n. W1, p. W593, doi. 10.1093/nar/gkad337
By:
- Mohamed, Ahmed;
- Bhuva, Dharmesh D;
- Lee, Sam;
- Liu, Ning;
- Tan, Chin Wee;
- Davis, Melissa J
Publication type:
Article
Mathematical model of TGF-β signalling: feedback coupling is consistent with signal switching.
Published in:
BMC Systems Biology, 2017, v. 11, p. 1, doi. 10.1186/s12918-017-0421-5
By:
- Khatibi, Shabnam;
- Hong-Jian Zhu;
- Wagner, John;
- Chin Wee Tan;
- Manton, Jonathan H.;
- Burgess, Antony W.
Publication type:
Article
Analysis of Wnt signaling β-catenin spatial dynamics in HEK293T cells.
Published in:
BMC Systems Biology, 2014, v. 8, n. 1, p. 1, doi. 10.1186/1752-0509-8-44
By:
- Chin Wee Tan;
- Gardiner, Bruce S.;
- Yumiko Hirokawa;
- Smith, David W.;
- Burgess, Antony W.
Publication type:
Article
vissE: a versatile tool to identify and visualise higher-order molecular phenotypes from functional enrichment analysis.
Published in:
BMC Bioinformatics, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12859-024-05676-y
By:
- Bhuva, Dharmesh D.;
- Tan, Chin Wee;
- Liu, Ning;
- Whitfield, Holly J.;
- Papachristos, Nicholas;
- Lee, Samuel C.;
- Kharbanda, Malvika;
- Mohamed, Ahmed;
- Davis, Melissa J.
Publication type:
Article
Transplantable programmed death ligand 1 expressing gastroids from gastric cancer prone Nfkb1<sup>−/−</sup> mice.
Published in:
Cell Death & Disease, 2021, v. 12, n. 12, p. 1, doi. 10.1038/s41419-021-04376-2
By:
- Low, Jun T.;
- Ho, Gwo-Yaw;
- Scott, Mark;
- Tan, Chin Wee;
- Whitehead, Lachlan;
- Barber, Kathy;
- Yip, Hon Y. K.;
- Dekkers, Johanna F.;
- Hirokawa, Yumiko;
- Silke, John;
- Burgess, Antony W.;
- Strasser, Andreas;
- Putoczki, Tracy L.;
- O'Reilly, Lorraine A.
Publication type:
Article
Sparse tensor product finite element method for nonlinear multiscale variational inequalities of monotone type.
Published in:
IMA Journal of Numerical Analysis, 2020, v. 40, n. 3, p. 1875, doi. 10.1093/imanum/drz011
By:
- Tan, Wee Chin;
- Hoang, Viet Ha
Publication type:
Article
Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt–b-catenin–mediated intestinal tumor growth and regeneration.
Published in:
Science Signaling, 2014, v. 7, n. 345, p. 1, doi. 10.1126/scisignal.2005411
By:
- Phesse, Toby J.;
- Buchert, Michael;
- Stuart, Emma;
- Flanagan, Dustin J.;
- Faux, Maree;
- Afshar-Sterle, Shoukat;
- Walker, Francesca;
- Hui-Hua Zhang;
- Nowell, Cameron J.;
- Jorissen, Robert;
- Chin Wee Tan;
- Yumiko Hirokawa;
- Eissmann, Moritz F.;
- Poh, Ashleigh R.;
- Malaterre, Jordane;
- Pearson, Helen B.;
- Kirsch, David G.;
- Provero, Paolo;
- Poli, Valeria;
- Ramsay, Robert G.
Publication type:
Article
Exploring the Singapore general population's trust in COVID-19 information from different sources and its association with perceived risk of infection during the pandemic.
Published in:
Frontiers in Public Health, 2024, p. 1, doi. 10.3389/fpubh.2024.1323543
By:
- Devi, Fiona;
- Chin Wee Tan, Bernard;
- Shafie, Saleha;
- Yun Jue Zhang;
- Shahwan, Shazana;
- Satghare, Pratika;
- Siow Ann Chong;
- Subramaniam, Mythily
Publication type:
Article
Essentially optimal finite elements for multiscale elliptic eigenvalue problems.
Published in:
Advances in Computational Mathematics, 2021, v. 47, n. 6, p. 1, doi. 10.1007/s10444-021-09903-5
By:
- Muoi, Pham Quy;
- Tan, Wee Chin;
- Hoang, Viet Ha
Publication type:
Article
High dimensional finite elements for time-space multiscale parabolic equations.
Published in:
Advances in Computational Mathematics, 2019, v. 45, n. 3, p. 1291, doi. 10.1007/s10444-018-09657-7
By:
- Tan, Wee Chin;
- Hoang, Viet Ha
Publication type:
Article
Spatial dynamics of tertiary lymphoid aggregates in head and neck cancer: insights into immunotherapy response.
Published in:
Journal of Translational Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12967-024-05409-y
By:
- Sadeghirad, Habib;
- Monkman, James;
- Tan, Chin Wee;
- Liu, Ning;
- Yunis, Joseph;
- Donovan, Meg L.;
- Moradi, Afshin;
- Jhaveri, Niyati;
- Perry, Chris;
- Adams, Mark N.;
- O’Byrne, Ken;
- Warkiani, Majid E.;
- Ladwa, Rahul;
- Hughes, Brett G.M.;
- Kulasinghe, Arutha
Publication type:
Article
Colon Cryptogenesis: Asymmetric Budding.
Published in:
PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0078519
By:
- Tan, Chin Wee;
- Hirokawa, Yumiko;
- Gardiner, Bruce S.;
- Smith, David W.;
- Burgess, Antony W.
Publication type:
Article
Wnt Signalling Pathway Parameters for Mammalian Cells.
Published in:
PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031882
By:
- Chin Wee Tan;
- Gardiner, Bruce S.;
- Hirokawa, Yumiko;
- Layton, Meredith J.;
- Smith, David W.;
- Burgess, Antony W.
Publication type:
Article
Dissection of the bone marrow microenvironment in hairy cell leukaemia identifies prognostic tumour and immune related biomarkers.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-98536-1
By:
- Koldej, Rachel M.;
- Prabahran, Ashvind;
- Tan, Chin Wee;
- Ng, Ashley P.;
- Davis, Melissa J.;
- Ritchie, David S.
Publication type:
Article
Transcriptomic profiling of cardiac tissues from SARS‐CoV‐2 patients identifies DNA damage.
Published in:
Immunology, 2023, v. 168, n. 3, p. 403, doi. 10.1111/imm.13577
By:
- Kulasinghe, Arutha;
- Liu, Ning;
- Tan, Chin Wee;
- Monkman, James;
- Sinclair, Jane E.;
- Bhuva, Dharmesh D.;
- Godbolt, David;
- Pan, Liuliu;
- Nam, Andy;
- Sadeghirad, Habib;
- Sato, Kei;
- Bassi, Gianluigi Li;
- O'Byrne, Ken;
- Hartmann, Camila;
- dos Santos Miggiolaro, Anna Flavia Ribeiro;
- Marques, Gustavo Lenci;
- Moura, Lidia Zytynski;
- Richard, Derek;
- Adams, Mark;
- de Noronha, Lucia
Publication type:
Article
Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine.
Published in:
Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02607-y
By:
- Hirokawa, Yumiko;
- Clarke, Jordan;
- Palmieri, Michelle;
- Tan, Tao;
- Mouradov, Dmitri;
- Li, Shan;
- Lin, Cong;
- Li, Fuqiang;
- Luo, Huijuan;
- Wu, Kui;
- Faux, Maree;
- Tan, Chin Wee;
- Lee, Margaret;
- Gard, Grace;
- Gibbs, Peter;
- Burgess, Antony W.;
- Sieber, Oliver M.
Publication type:
Article
Colon organoid formation and cryptogenesis are stimulated by growth factors secreted from myofibroblasts.
Published in:
PLoS ONE, 2018, v. 13, n. 6, p. 1, doi. 10.1371/journal.pone.0199412
By:
- Yip, Hon Yan Kelvin;
- Tan, Chin Wee;
- Hirokawa, Yumiko;
- Burgess, Antony Wilks
Publication type:
Article
Specification, annotation, visualization and simulation of a large rule-based model for ERBB receptor signaling.
Published in:
BMC Systems Biology, 2012, v. 6, n. 1, p. 107, doi. 10.1186/1752-0509-6-107
By:
- Creamer, Matthew S.;
- Stites, Edward C.;
- Aziz, Meraj;
- Cahill, James A.;
- Chin Wee Tan;
- Berens, Michael E.;
- Haiyong Han;
- Bussey, Kimberley J.;
- Von Hoff, Daniel D.;
- Hlavacek, William S.;
- Posner, Richard G.
Publication type:
Article
Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth.
Published in:
EMBO Molecular Medicine, 2019, v. 11, n. 4, p. N.PAG, doi. 10.15252/emmm.201809539
By:
- Thilakasiri, Pathum;
- Huynh, Jennifer;
- Poh, Ashleigh R;
- Tan, Chin Wee;
- Nero, Tracy L;
- Tran, Kelly;
- Parslow, Adam C;
- Afshar‐Sterle, Shoukat;
- Baloyan, David;
- Hannan, Natalie J;
- Buchert, Michael;
- Scott, Andrew Mark;
- Griffin, Michael DW;
- Hollande, Frederic;
- Parker, Michael W;
- Putoczki, Tracy L;
- Ernst, Matthias;
- Chand, Ashwini L
Publication type:
Article
Library size confounds biology in spatial transcriptomics data.
Published in:
Genome Biology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s13059-024-03241-7
By:
- Bhuva, Dharmesh D.;
- Tan, Chin Wee;
- Salim, Agus;
- Marceaux, Claire;
- Pickering, Marie A.;
- Chen, Jinjin;
- Kharbanda, Malvika;
- Jin, Xinyi;
- Liu, Ning;
- Feher, Kristen;
- Putri, Givanna;
- Tilley, Wayne D.;
- Hickey, Theresa E.;
- Asselin-Labat, Marie-Liesse;
- Phipson, Belinda;
- Davis, Melissa J.
Publication type:
Article
Discrete Element Framework for Modelling Extracellular Matrix, Deformable Cells and Subcellular Components.
Published in:
PLoS Computational Biology, 2015, v. 11, n. 10, p. 1, doi. 10.1371/journal.pcbi.1004544
By:
- Gardiner, Bruce S.;
- Wong, Kelvin K. L.;
- Joldes, Grand R.;
- Rich, Addison J.;
- Tan, Chin Wee;
- Burgess, Antony W.;
- Smith, David W.
Publication type:
Article

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