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- Title
Different types of postmenopausal hormone therapy and mammographic density in Norwegian women.
- Authors
Bremnes, Yngve; Ursin, Giske; Bjurstam, Nils; Lund, Eiliv; Gram, Inger Torhild
- Abstract
Postmenopausal hormone therapy (HT) is associated with increased risk of breast cancer. The HTs used in Scandinavia is associated with higher risk estimates than those used in most other countries. Mammographic density is one of the strongest risk factors for breast cancer, and possibly an intermediate marker for breast cancer. We decided to examine the relationship between use of different types of HT and mammographic density in Norwegian women. Altogether, 1,007 postmenopausal participants in the governmental mammographic screening program were asked about current and previous HT use. Mammograms were classified according to percent and absolute mammographic density. Overall, current users of HT had on average 3.6% higher mean percent mammographic density when compared with never users ( p < 0.001). After adjustment for age at screening, number of children and BMI in a multivariate model, women using the continuous estradiol (E
- Publication
International Journal of Cancer, 2007, Vol 120, Issue 4, p880
- ISSN
0020-7136
- Publication type
Article
- DOI
10.1002/ijc.22437