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Dyslipidemia, Insulin Resistance, Ectopic Lipid Accumulation, and Vascular Function in Resistance to Thyroid Hormone β.
Published in:
2021
By:
- Moran, Carla;
- McEniery, Carmel M.;
- Schoenmakers, Nadia;
- Mitchell, Catherine;
- Sleigh, Alison;
- Watson, Laura;
- Lyons, Greta;
- Burling, Keith;
- Barker, Peter;
- Chatterjee, Krishna
Publication type:
journal article
Mitochondrial dysfunction in patients with primary congenital insulin resistance.
Published in:
2011
By:
- Sleigh, Alison;
- Raymond-Barker, Philippa;
- Thackray, Kerrie;
- Porter, David;
- Hatunic, Mensud;
- Vottero, Alessandra;
- Burren, Christine;
- Mitchell, Catherine;
- McIntyre, Martin;
- Brage, Soren;
- Carpenter, T. Adrian;
- Murgatroyd, Peter R.;
- Brindle, Kevin M.;
- Kemp, Graham J.;
- O'Rahilly, Stephen;
- Semple, Robert K.;
- Savage, David B.
Publication type:
journal article
Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis.
Published in:
2009
By:
- Semple, Robert K.;
- Sleigh, Alison;
- Murgatroyd, Peter R.;
- Adams, Claire A.;
- Bluck, Les;
- Jackson, Sarah;
- Vottero, Alessandra;
- Kanabar, Dipak;
- Charlton-Menys, Valentine;
- Durrington, Paul;
- Soos, Maria A.;
- Carpenter, T. Adrian;
- Lomas, David J.;
- Cochran, Elaine K.;
- Gorden, Phillip;
- O'Rahilly, Stephen;
- Savage, David B.
Publication type:
journal article
Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression.
Published in:
eLife, 2017, p. 1, doi. 10.7554/eLife.23813.001
By:
- Rocha, Nuno;
- Bulger, David A.;
- Frontini, Andrea;
- Titheradge, Hannah;
- Gribsholt, Sigrid Bjerge;
- Knox, Rachel;
- Page, Matthew;
- Harris, Julie;
- Payne, Felicity;
- Adams, Claire;
- Sleigh, Alison;
- Crawford, John;
- Gjesing, Anette Prior;
- Bork-Jensen, Jette;
- Pedersen, Oluf;
- Barroso, Inês;
- Hansen, Torben;
- Cox, Helen;
- Reilly, Mary;
- Rossor, Alex
Publication type:
Article
Constitutive Activation of AKT2 in Humans Leads to Hypoglycemia Without Fatty Liver or Metabolic Dyslipidemia.
Published in:
2017
By:
- Minic, Marina;
- Rocha, Nuno;
- Harris, Julie;
- Groeneveld, Matthijs P;
- Leiter, Sarah;
- Wareham, Nicholas;
- Sleigh, Alison;
- De Lonlay, Pascale;
- Hussain, Khalid;
- O'Rahilly, Stephen;
- Semple, Robert K
Publication type:
journal article
Low circulating levels of IGF-1 in healthy adults are associated with reduced β-cell function, increased intramyocellular lipid, and enhanced fat utilization during fasting.
Published in:
2014
By:
- Thankamony, Ajay;
- Capalbo, Donatella;
- Marcovecchio, M Loredana;
- Sleigh, Alison;
- Jørgensen, Sine Wanda;
- Hill, Nathan R;
- Mooslehner, Katrin;
- Yeo, Giles S H;
- Bluck, Les;
- Juul, Anders;
- Vaag, Allan;
- Dunger, David B
Publication type:
journal article
Mitochondrial oxidative phosphorylation is impaired in patients with congenital lipodystrophy.
Published in:
2012
By:
- Sleigh A;
- Stears A;
- Thackray K;
- Watson L;
- Gambineri A;
- Nag S;
- Campi VI;
- Schoenmakers N;
- Brage S;
- Carpenter TA;
- Murgatroyd PR;
- O'Rahilly S;
- Kemp GJ;
- Savage DB;
- Sleigh, Alison;
- Stears, Anna;
- Thackray, Kerrie;
- Watson, Laura;
- Gambineri, Alessandra;
- Nag, Sath
Publication type:
journal article
Simple and effective exercise design for assessing in vivo mitochondrial function in clinical applications using 31P magnetic resonance spectroscopy.
Published in:
Scientific Reports, 2016, p. 19057, doi. 10.1038/srep19057
By:
- Sleigh, Alison;
- Lupson, Victoria;
- Thankamony, Ajay;
- Dunger, David B.;
- Savage, David B.;
- Carpenter, T. Adrian;
- Kemp, Graham J.
Publication type:
Article
Defective Mitochondrial Function In Vivo in Skeletal Muscle in Adults with Down’s Syndrome: A 31P-MRS Study.
Published in:
PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0084031
By:
- Phillips, Alexander C.;
- Sleigh, Alison;
- McAllister, Catherine J.;
- Brage, Soren;
- Carpenter, T. Adrian;
- Kemp, Graham J.;
- Holland, Anthony J.
Publication type:
Article
Association of insulin resistance with the accumulation of saturated intramyocellular lipid: A comparison with other fat stores.
Published in:
NMR in Biomedicine, 2024, v. 37, n. 8, p. 1, doi. 10.1002/nbm.5117
By:
- Azhar, Mueed;
- Watson, Laura P. E.;
- De Lucia Rolfe, Emanuella;
- Ferraro, Michele;
- Carr, Katherine;
- Worsley, Jieniean;
- Boesch, Chris;
- Hodson, Leanne;
- Chatterjee, Krishna K.;
- Kemp, Graham J.;
- Savage, David B.;
- Sleigh, Alison
Publication type:
Article
31P magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations.
Published in:
NMR in Biomedicine, 2021, v. 34, n. 5, p. 1, doi. 10.1002/nbm.4246
By:
- Meyerspeer, Martin;
- Boesch, Chris;
- Cameron, Donnie;
- Dezortová, Monika;
- Forbes, Sean C.;
- Heerschap, Arend;
- Jeneson, Jeroen A.L.;
- Kan, Hermien E.;
- Kent, Jane;
- Layec, Gwenaël;
- Prompers, Jeanine J.;
- Reyngoudt, Harmen;
- Sleigh, Alison;
- Valkovič, Ladislav;
- Kemp, Graham J.;
- Baligand, Céline;
- Carlier, Pierre G.;
- Chatel, Benjamin;
- Damon, Bruce;
- Heskamp, Linda
Publication type:
Article
MRI basic principles and applications. 3rd edn, by Mark A. Brown and Richard C. Semelka. Wiley-Liss, Chichester, £32.50.
Published in:
NMR in Biomedicine, 2004, v. 17, n. 4, p. 209, doi. 10.1002/nbm.864
By:
- Sleigh, Alison
Publication type:
Article
Abdominal fat depots associated with insulin resistance and metabolic syndrome risk factors in black African young adults.
Published in:
2015
By:
- De Lucia Rolfe, Emanuella;
- Ong, Ken K.;
- Sleigh, Alison;
- Dunge, David B.;
- Norris, Shane A.;
- Dunger, David B
Publication type:
journal article
Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Older Individuals.
Published in:
International Journal of Endocrinology, 2013, p. 1, doi. 10.1155/2013/870487
By:
- Finucane, Francis M.;
- Sharp, Stephen J.;
- Hatunic, Mensud;
- Sleigh, Alison;
- De Lucia Rolfe, Ema;
- Sayer, Avan Aihie;
- Cooper, Cyrus;
- Griffin, Simon J.;
- Savage, David B.;
- Wareham, Nicholas J.
Publication type:
Article
Validity of ultrasonography to assess hepatic steatosis compared to magnetic resonance spectroscopy as a criterion method in older adults.
Published in:
PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0207923
By:
- De Lucia Rolfe, Emanuella;
- Brage, Soren;
- Sleigh, Alison;
- Finucane, Francis;
- Griffin, Simon J.;
- Wareham, Nick J.;
- Ong, Ken K.;
- Forouhi, Nita G.
Publication type:
Article
Validation of Ultrasound Estimates of Visceral Fat in Black South African Adolescents.
Published in:
Obesity (19307381), 2011, v. 19, n. 9, p. 1892, doi. 10.1038/oby.2011.213
By:
- De Lucia Rolfe, Emanuella;
- Norris, Shane A.;
- Sleigh, Alison;
- Brage, Soren;
- Dunger, David B.;
- Stolk, Ronald P.;
- Ong, Ken K.
Publication type:
Article
Ultrasound Measurements of Visceral and Subcutaneous Abdominal Thickness to Predict Abdominal Adiposity Among Older Men and Women.
Published in:
Obesity (19307381), 2010, v. 18, n. 3, p. 625, doi. 10.1038/oby.2009.309
By:
- Rolfe, Ema De Lucia;
- Sleigh, Alison;
- Finucane, Francis M.;
- Brage, Soren;
- Stolk, Ronald P.;
- Cooper, Cyrus;
- Sharp, Stephen J.;
- Wareham, Nicholas J.;
- Ong, Ken K.
Publication type:
Article
Familial adult onset hyperinsulinism due to an activating glucokinase mutation: implications for pharmacological glucokinase activation.
Published in:
Clinical Endocrinology, 2014, v. 81, n. 6, p. 855, doi. 10.1111/cen.12517
By:
- Challis, Benjamin G.;
- Harris, Julie;
- Sleigh, Alison;
- Isaac, Iona;
- Orme, Steve M.;
- Seevaratnam, Nandini;
- Dhatariya, Ketan;
- Simpson, Helen L.;
- Semple, Robert K.
Publication type:
Article
Assessing Metabolism and injury in Acute Human Traumatic Brain injury with Magnetic Resonance Spectroscopy: Current and Future Applications.
Published in:
Frontiers in Neurology, 2017, p. 1, doi. 10.3389/fneur.2017.00426
By:
- Stovell, Matthew G.;
- Jiun-Lin Yan;
- Sleigh, Alison;
- Mada, Marius O.;
- Carpenter, T. Adrian;
- Hutchinson, Peter J. A.;
- Carpenter, Keri L. H.
Publication type:
Article

Found: 19

Dyslipidemia, Insulin Resistance, Ectopic Lipid Accumulation, and Vascular Function in Resistance to Thyroid Hormone β.

Mitochondrial dysfunction in patients with primary congenital insulin resistance.

Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis.

Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression.

Constitutive Activation of AKT2 in Humans Leads to Hypoglycemia Without Fatty Liver or Metabolic Dyslipidemia.

Low circulating levels of IGF-1 in healthy adults are associated with reduced β-cell function, increased intramyocellular lipid, and enhanced fat utilization during fasting.

Mitochondrial oxidative phosphorylation is impaired in patients with congenital lipodystrophy.

Simple and effective exercise design for assessing in vivo mitochondrial function in clinical applications using <sup>31</sup>P magnetic resonance spectroscopy.

Defective Mitochondrial Function <i>In Vivo</i> in Skeletal Muscle in Adults with Down’s Syndrome: A <sup>31</sup>P-MRS Study.

Association of insulin resistance with the accumulation of saturated intramyocellular lipid: A comparison with other fat stores.

<sup>31</sup>P magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations.

MRI basic principles and applications. 3rd edn, by Mark A. Brown and Richard C. Semelka. Wiley-Liss, Chichester, £32.50.

Abdominal fat depots associated with insulin resistance and metabolic syndrome risk factors in black African young adults.

Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Older Individuals.

Validity of ultrasonography to assess hepatic steatosis compared to magnetic resonance spectroscopy as a criterion method in older adults.

Validation of Ultrasound Estimates of Visceral Fat in Black South African Adolescents.

Ultrasound Measurements of Visceral and Subcutaneous Abdominal Thickness to Predict Abdominal Adiposity Among Older Men and Women.

Familial adult onset hyperinsulinism due to an activating glucokinase mutation: implications for pharmacological glucokinase activation.

Assessing Metabolism and injury in Acute Human Traumatic Brain injury with Magnetic Resonance Spectroscopy: Current and Future Applications.