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Topoisomerase II and leukemia.
Published in:
Annals of the New York Academy of Sciences, 2014, v. 1310, n. 1, p. 98, doi. 10.1111/nyas.12358
By:
- Pendleton, MaryJean;
- Lindsey, R. Hunter;
- Felix, Carolyn A.;
- Grimwade, David;
- Osheroff, Neil
Publication type:
Article
Reciprocal DNA topoisomerase II cleavage events at 5'-TATTA-3' sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing.
Published in:
Oncogene, 2003, v. 22, n. 52, p. 8448, doi. 10.1038/sj.onc.1207052
By:
- Whitmarsh, Ryan J.;
- Saginario, Charles;
- Zhuo, Ya;
- Hilgenfeld, Eva;
- Rappaport, Eric F.;
- Megonigal, Maureen D.;
- Carroll, Martin;
- Liu, Mingli;
- Osheroff, Neil;
- Cheung, Nai-Kong V.;
- Slater, Diana J.;
- Ried, Thomas;
- Knutsen, Turid;
- Blair, Ian A.;
- Felix, Carolyn A.
Publication type:
Article
MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisomerase.
Published in:
Oncogene, 2002, v. 21, n. 30, p. 4706, doi. 10.1038/sj.onc.1205572
By:
- Slater, Diana J.;
- Hilgenfeld, Eva;
- Rappaport, Eric F.;
- Shah, Narayan;
- Meek, Rita G.;
- Williams, Wendy Reed;
- Lovett, Brian D.;
- Osheroff, Neil;
- Autar, Reshma S.;
- Ried, Thomas;
- Felix, Carolyn A.
Publication type:
Article
Molecular Pathogenesis of Secondary Acute Promyelocytic Leukemia.
Published in:
Mediterranean Journal of Hematology & Infectious Diseases, 2011, v. 3, n. 1, p. 1, doi. 10.4084/MJHID.2011.045
By:
- Joannides, Melanie;
- Mays, Ashley N.;
- Mistry, Anita R.;
- Hasan, Syed Khizer;
- Reiter, Andreas;
- Wiemels, Joseph L.;
- Felix, Carolyn A.;
- Coco, Francesco Lo;
- Osheroff, Neil;
- Solomon, Ellen;
- Grimwade, David
Publication type:
Article
Simultaneous determination of etoposide and its catechol metabolite in the plasma of pediatric patients by liquid chromatography/tandem mass spectrometry.
Published in:
Journal of Mass Spectrometry, 2001, v. 36, n. 7, p. 771, doi. 10.1002/jms.173
By:
- Pang, Shaokun;
- Zheng, Naiyu;
- Felix, Carolyn A.;
- Scavuzzo, Jennifer;
- Boston, Ray;
- Blair, Ian A.
Publication type:
Article
mll ortholog containing functional domains of human MLL is expressed throughout the zebrafish lifespan and in haematopoietic tissues.
Published in:
British Journal of Haematology, 2011, v. 152, n. 3, p. 307, doi. 10.1111/j.1365-2141.2010.08398.x
By:
- Robinson, Blaine W.;
- Germano, Giuseppe;
- Song, Yuanquan;
- Abrams, Joshua;
- Scott, Marion;
- Guariento, Ilaria;
- Tiso, Natascia;
- Argenton, Francesco;
- Basso, Giuseppe;
- Rhodes, Jennifer;
- Kanki, John P.;
- Look, A. Thomas;
- Balice-Gordon, Rita J.;
- Felix, Carolyn A.
Publication type:
Article
Inhibiting cytosolic translation and autophagy improves health in mitochondrial disease.
Published in:
Human Molecular Genetics, 2015, v. 24, n. 17, p. 4829, doi. 10.1093/hmg/ddv207
By:
- Min Peng;
- Ostrovsky, Julian;
- Young Joon Kwon;
- Polyak, Erzsebet;
- Licata, Joseph;
- Mai Tsukikawa;
- Marty, Eric;
- Thomas, Jeffrey;
- Felix, Carolyn A.;
- Rui Xiao;
- Zhe Zhang;
- Gasser, David L.;
- Argon, Yair;
- Falk, Marni J.
Publication type:
Article
KMT2A‐MAML2 rearrangement emerged and regressed during neuroblastoma therapy without leukemia after 12.8‐year follow‐up.
Published in:
Pediatric Blood & Cancer, 2022, v. 69, n. 1, p. 1, doi. 10.1002/pbc.29344
By:
- Felix, Carolyn A.;
- Slater, Diana J.;
- Davenport, James W.;
- Yu, Xiang;
- Gregory, Brian D.;
- Li, Marilyn M.;
- Rappaport, Eric F.;
- Cheung, Nai‐Kong V.
Publication type:
Article
Unique Familial MLL(KMT2A)-Rearranged Precursor B-Cell Infant Acute Lymphoblastic Leukemia in Non-twin Siblings.
Published in:
2016
By:
- Urtishak, Karen A.;
- Robinson, Blaine W.;
- Rappaport, Eric F.;
- Sarezky, Margaret D.;
- Biegel, Jaclyn A.;
- Nichols, Kim E.;
- Wilmoth, Donna M.;
- Wang, Li‐San;
- Stern, Julie W.;
- Felix, Carolyn A.;
- Wang, Li-San
Publication type:
journal article
Intensified chemotherapy without SCT in infant ALL: Results from COG P9407 (Cohort 3).
Published in:
Pediatric Blood & Cancer, 2015, v. 62, n. 3, p. 419, doi. 10.1002/pbc.25322
By:
- Dreyer, ZoAnn E.;
- Hilden, Joanne M.;
- Jones, Tamekia L.;
- Devidas, Meenakshi;
- Winick, Naomi J.;
- Willman, Cheryl L.;
- Harvey, Richard C.;
- Chen, I‐Ming;
- Behm, Fred G.;
- Pullen, Jeanette;
- Wood, Brent L.;
- Carroll, Andrew J.;
- Heerema, Nyla A.;
- Felix, Carolyn A.;
- Robinson, Blaine;
- Reaman, Gregory H.;
- Salzer, Wanda L.;
- Hunger, Stephen P.;
- Carroll, William L.;
- Camitta, Bruce M.
Publication type:
Article
Infant leukemia 2010: A call to action for the west and the 'four Asian Tigers'.
Published in:
Pediatric Blood & Cancer, 2010, v. 55, n. 7, p. 1247, doi. 10.1002/pbc.22817
By:
- Felix, Carolyn A.
Publication type:
Article
A safer regimen for high-risk neuroblastoma.
Published in:
Pediatric Blood & Cancer, 2009, v. 53, n. 1, p. 3, doi. 10.1002/pbc.22020
By:
- Felix, Carolyn A.
Publication type:
Article
Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia.
Published in:
Nature Genetics, 1999, v. 23, n. 2, p. 166, doi. 10.1038/13793
By:
- Song, Woo-Joo;
- Sullivan, Melanie G.;
- Legare, Robert D.;
- Hutchings, Sarah;
- Tan, Xiaolian;
- Kufrin, Dubravka;
- Ratajczak, Janina;
- Resende, Isabel C.;
- Haworth, Catherine;
- Hock, Randy;
- Loh, Mignon;
- Felix, Carolyn;
- Roy, Denis-Claude;
- Busque, Lambert;
- Kurnit, David;
- Willman, Cheryl;
- Gewirtz, Alan M.;
- Speck, Nancy A.;
- Bushweller, John H.
Publication type:
Article
BglII‐based panhandle and reverse panhandle PCR approaches increase capability for cloning der(II) and der(other) genomic breakpoint junctions of MLL translocationsAll new sequences described herein were deposited in GenBank (GenBank Nos. DQ387204, DQ387205, and DQ387206).
Published in:
Genes, Chromosomes & Cancer, 2006, v. 45, n. 8, p. 740, doi. 10.1002/gcc.20336
By:
- Blaine W. Robinson;
- Diana J. Slater;
- Carolyn A. Felix
Publication type:
Article
Potential role for DNA topoisomerase II poisons in the generation of t(11;20)(p15;q11) translocations.
Published in:
Genes, Chromosomes & Cancer, 2000, v. 29, n. 2, p. 96, doi. 10.1002/1098-2264(2000)9999:9999<::AID-GCC1013>3.0.CO;2-T
By:
- Ahuja, Harish G.;
- Felix, Carolyn A.;
- Aplan, Peter D.
Publication type:
Article
RAS mutations in pediatric leukemias with MLL gene rearrangements.
Published in:
Genes, Chromosomes & Cancer, 1998, v. 21, n. 3, p. 270, doi. 10.1002/(SICI)1098-2264(199803)21:3<270::AID-GCC14>3.0.CO;2-T
By:
- Mahgoub, Nidal;
- Parker, Robert I.;
- Hosler, Matthew R.;
- Close, Pamelyn;
- Winick, Naomi J.;
- Masterson, Margaret;
- Shannon, Kevin M.;
- Felix, Carolyn A.
Publication type:
Article
Leukemia‐associated transcription factor mllt3 is important for primitive erythroid development in zebrafish embryogenesis.
Published in:
Developmental Dynamics, 2022, v. 251, n. 10, p. 1728, doi. 10.1002/dvdy.477
By:
- Germano, Giuseppe;
- Porazzi, Patrizia;
- Felix, Carolyn A.
Publication type:
Article
Potential role for wild-type p53 in leukemias with MLL gene translocations.
Published in:
Oncogene, 1998, v. 16, n. 10, p. 1351, doi. 10.1038/sj.onc.1201637
By:
- Megonigal, Maureen D;
- Rappaport, Eric F;
- Nowell, Peter C;
- Lange, Beverly J;
- Felix, Carolyn A
Publication type:
Article
Overexpression of p53 Protein in Cutaneous T Cell Lymphoma: Relationship to Large...
Published in:
Journal of Investigative Dermatology, 1998, v. 110, n. 5, p. 767, doi. 10.1046/j.1523-1747.1998.00167.x
By:
- Li, Guoqing;
- Chooback, Lilian;
- Wolfe, Jonathan T.;
- Rook, Alain H.;
- Felix, Carolyn A.;
- Lessin, Stuart R.;
- Salhany, Kevin E.
Publication type:
Article
Abundant anti-apoptotic BCL-2 is a molecular target in leukaemias with t(4;11) translocation.
Published in:
British Journal of Haematology, 2008, v. 141, n. 6, p. 827, doi. 10.1111/j.1365-2141.2008.07100.x
By:
- Robinson, Blaine W.;
- Behling, Kathryn C.;
- Gupta, Manish;
- Zhang, Alena Y.;
- Moore, Jonni S.;
- Bantly, Andrew D.;
- Willman, Cheryl L.;
- Carroll, Andrew J.;
- Adamson, Peter C.;
- Barrett, Jeffrey S.;
- Felix, Carolyn A.
Publication type:
Article

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