Presents a study that examined the effect of 2-methoxyestradiol (2-ME) on apoptosis in a panel of pancreatic cancer cell lines. Categories of pancreatic cancer cell lines; Importance of apoptosis to multicellular organisms; Role of mitochondria in cell death; Functions of the pro-apoptotic members of Bcl-2 family; Background on the anti-proliferative activity of 2-ME.