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- Title
Effects of a Raisin Supplement on Cognitive Performance, Quality of Life, and Functional Activities in Healthy Older Adults—Randomized Clinical Trial.
- Authors
Rodrigo-Gonzalo, María José; González-Manzano, Susana; Pablos-Hernández, María Carmen; Méndez-Sánchez, Roberto; Ayuda Duran, Begoña; González-Sánchez, Jesús; Barbero-Iglesias, Fausto; González-Paramás, Ana María; Recio-Rodríguez, José Ignacio
- Abstract
The objective of this study was to evaluate the effects of consuming 50 g of raisins on cognitive performance, quality of life, and functional activities in healthy older adults. This is a parallel randomized controlled clinical trial, in which 80 subjects over 70 years of age participated. For 6 months, the intervention group (IG; n = 40) consumed 50 g of raisins per day added to their usual diet, whereas the control group (CG; n = 40) received no supplement. All variables were measured at baseline and at 6 months. Cognitive performance assessed with the Montreal Cognitive Assessment (MOCA) test shows a difference of 3.27 points (95% CI 1.59 to 4.96), p ≤ 0.001, favorable to the IG, after the intervention. Among the cognitive performances, an improvement is observed in the IG in orientation, assessed both with the MOCA test 0.49 (95% CI 0.10 to 0.87), p = 0.014, and with the Mini-Mental State Examination (MMSE) test, 0.36 (95% CI 0.02 to 0.70), p = 0.038. In visuospatial/executive capacity and in language, improvements were also observed in the IG, 1.36 (95% CI 0.77 to 1.95), p = 0.001, and 0.54 points (95% CI 0.12 to 0.96), p = 0.014, respectively. Immediate and delayed recall, assessed with the Rey Auditory Verbal Learning Test, improved in the IG. In addition, the IG showed a better quality of life and greater autonomy in instrumental activities of daily living after 6 months. No significant changes were observed in the rest of the variables analyzed. Therefore, the consumption of 50 g of raisins produces a slight improvement in cognitive performance, quality of life, and functional activities in the elderly.
- Subjects
MEMORY; CONFIDENCE intervals; FUNCTIONAL status; GRAPES; ACTIVITIES of daily living; DIETARY supplements; TREATMENT effectiveness; RANDOMIZED controlled trials; NEUROPSYCHOLOGICAL tests; QUALITY of life; QUESTIONNAIRES; RESEARCH funding; DESCRIPTIVE statistics; COGNITIVE testing; STATISTICAL sampling
- Publication
Nutrients, 2023, Vol 15, Issue 12, p2811
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu15122811