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- Title
Antimicrobial Potential of Methanolic Extracts from Betonica bulgarica Degen et Neič. (Lamiaceae).
- Authors
Dinev, Toncho G.; Rusenova, Nikolina V.; Tzanova, Milena T.; Grozeva, Neli H.; Gerdzhikova, Mariya A.; Stoyanov, Plamen S.; Mladenova, Tsvetelina R.; Beev, Georgi G.
- Abstract
Betonica bulgarica Degen et Neič. (syn. Stachys bulgarica Hayek) is a Bulgarian endemic plant included in Red Data Book of Bulgaria under the category "endangered". The aim of the present study is to provide data about the antimicrobial activity of B. bulgarica leaf, flower, seed, stem and root methanolic extracts against Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, Bacillus cereus, Aspergillus ochraceus 2002 IM-BAS, Fusarium moniliforme 394 FN-9, Fusarium graminearum 2294 IMI 155426 and Penicillium verrucosum 2003 NRRL F-143. Antimicrobial activity of the extracts was evaluated by agar well diffusion method. Root extracts of B. bulgarica exhibited the highest antibacterial activity against S. aureus and B. cereus with large zones of inhibition. All extracts demonstrated either low and statistically insignificant activity against E. coli or a lack thereof. As a whole, extracts of Ablanovo area (in Sinite kamani National Park) exerted the highest activity against S. aureus, B. cereus and E. coli. Leaf, flower, stem and root extracts of B. bulgarica showed either a lack of antifungal activity or low and statistically insignificant one.
- Subjects
BULGARIA; STACHYS; LAMIACEAE; ENDEMIC plants; METADATA; EXTRACTS; BACILLUS cereus
- Publication
Ecologia Balkanica, 2020, Vol 12, Issue 2, p165
- ISSN
1313-9940
- Publication type
Article