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- Title
Comparison of Therapeutic Plasma Exchange and Double Filtration Plasmapheresis: Five Year Experience of Nephrology Unit.
- Authors
Bek, Sibel Gokcay; Bakırdöğen, Serkan; Eren, Necmi; Hanazay, Yusuf; Gonullu, Betul Kalender
- Abstract
Objective: The aim of the study was to evaluate the outcomes and characteristics of therapeutic plasma exchange (TPE) and double filtration plasmapheresis (DFPP) in one center. Method: The data of cases treated with therapeutic plasmapheresis at the university hospital between 2007 and 2012 were retrospectively analyzed. 445 TPE and 391 DFPP sessions were done totally. Results: In the 5.5 years, in 116 cases 445 TPE and 391 DFPP sessions were done. The mean age was 46.61±16.83 years. There were 49 female and 67 male patients. Guillain-Barre syndrome (8.6%) was the commonly encountered indication for neurological diseases, glomerulonephritis (25%) was the leading indication for the renal-related diseases. Skin involvement due to diabetes mellitus (13.8%) and Pemphigus Vulgaris (5.2%) were the dermatological diseases. Complication rates were similar between DFPP and TPE sessions (p= 0.411). Conclusion: TPE and DFPP are safe and vital membrane separation techniques used as a treatment for a wide spectrum of diseases. These treatments can be safely done in hemodialysis units intensive care units and DFPP should be considered for the therapy refractory neurological diseases.
- Subjects
PLASMA exchange (Therapeutics); TREATMENT of Guillain-Barre syndrome; GLOMERULONEPHRITIS
- Publication
Dicle Medical Journal / Dicle Tip Dergisi, 2021, Vol 48, Issue 3, p523
- ISSN
1300-2945
- Publication type
Article
- DOI
10.5798/dicletip.988064