We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Versatile Synthesis of 1- O-(ω-Aminolauryl)-I(4,5)P<sub>2</sub>.
- Authors
Varvogli, Anastasia-Aikaterini C.; Fylaktakidou, Konstantina C.; Farmaki, Theodora; Stefanakis, John G.; Koumbis, Alexandros E.
- Abstract
The synthesis of a model 1- O-(ω-aminoacyl)-IP2 derivative, lauryl 4,5-bisphosphate 31, was realized following a versatile and high-yielding scheme. The flexible synthetic strategy used for this purpose allows the preparation of a range of other useful IP, IP2 and IP3 derivatives. In view of the central role played by IPs and PIPs in cellular life, the preparation of functionalized myo-inositol derivatives of this type may facilitate the isolation and fluorescent localization of related proteins.
- Publication
European Journal of Organic Chemistry, 2012, Vol 2012, Issue 29, p5855
- ISSN
1434-193X
- Publication type
Article
- DOI
10.1002/ejoc.201200726