We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Serological markers of hepatitis B and C in patients with HIV/AIDS and active tuberculosis.
- Authors
Araújo‐Mariz, Carolline; Lopes, Edmundo Pessoa; Ximenes, Ricardo A.A.; Lacerda, Heloísa R.; Miranda‐Filho, Demócrito B.; Montarroyos, Ulisses R.; Barreto, Silvana; Salustiano, Daniela Medeiros; Albuquerque, Maria Fátima Pessoa Militão
- Abstract
Infection with hepatitis B virus (HBV) and C virus (HCV) are common in patients with HIV/AIDS and tuberculosis (TB). This is a cross-sectional study with patients infected with HIV/AIDS and active TB in Recife, Brazil, aiming to verify the prevalence of markers for HBV: antibody to hepatitis B core antigen (anti-HBc); and HCV: antibody to hepatitis C virus (anti-HCV) by chemiluminescence, and to identify the frequency of associated factors. Data were collected through questionnaires, and blood was drawn from patients for analysis. We used the chi-square test and the Fisher exact test when necessary. We conducted a bivariate logistic regression analysis and the magnitude of the associations was expressed as odds ratio (OR) with a confidence interval of 95%. Among 166 patients studied with HIV/AIDS and active TB, anti-HBc was positive in 61 patients [36.7%; 95%CI (29.4-44.6%)] and anti-HCV in 11[6.6%; 95%CI (3.4-11.5%)]. In the logistic regression analysis, male sex, and age ≥40 years were independent factors associated with the occurrence of anti-HBc. In conclusion, we verified a high frequency of HBV contact marker and a low frequency of HCV markers in patients with HIV/AIDS and TB in Recife. J. Med. Virol. 88:996-1002, 2016. © 2015 Wiley Periodicals, Inc.
- Publication
Journal of Medical Virology, 2016, Vol 88, Issue 6, p996
- ISSN
0146-6615
- Publication type
Article
- DOI
10.1002/jmv.24432