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- Title
Daratumumab (Anti-CD38) for Treatment of Disseminated Nontuberculous Mycobacteria in a Patient With Anti–Interferon-γ Autoantibodies.
- Authors
Ochoa, Sebastian; Ding, Li; Kreuzburg, Samantha; Treat, Jennifer; Holland, Steven M; Zerbe, Christa S
- Abstract
Patients with autoantibodies to interferon-γ (IFN-γ) may develop severe nontuberculous mycobacterial infections. We describe the novel use of daratumumab in a patient with autoantibodies to IFN-γ who had progressive infection, resulting in clinical and radiographic improvement.
- Subjects
THERAPEUTIC use of monoclonal antibodies; AUTOANTIBODIES; INTERFERONS; TREATMENT effectiveness; MYCOBACTERIAL diseases; DISEASE risk factors
- Publication
Clinical Infectious Diseases, 2021, Vol 72, Issue 12, p2206
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciaa1086