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- Title
ADVANCED TREATMENT IN RHEUMATOID ARTHRITIS. IS IT POSSIBLE TO TAPER THE BIOLOGICAL TREATMENT?
- Authors
Cambu, Ina; Nuta, Catalina Raluca; Predeteanu, Denisa
- Abstract
Rheumatoid arthritis (RA) is a systemic autoimmune disease, leading to synovial hypertrophy and adjacent bone and cartilage destruction. The combined use of biological agents and methotrexate (MTX) has revolutionised the treatment of RA producing significant improvements in clinical, radiographic and functional outcomes. The results of clinical study and experience of the specialities of rheumatology in clinical statement showed the long treatment may be associated with side effects, in addition biological treatment means high cost. The next goal should be remission without the use of biological agents. That's why new treatment in RA means the tapering or even stopping the biological treatment in patients with RA who reached remission. In association with the new recommendation EULAR in 2013 there are many studies which showed the possibility of tapering or discontinuing the biological therapy in patients in sustained remission.
- Subjects
RHEUMATOID arthritis treatment; IMMUNOLOGIC diseases; LONG-term health care; DISEASE remission; HYPERTROPHY; DRUG side effects; MEDICAL care costs; METHOTREXATE
- Publication
Romanian Journal of Rheumatology / Revista Romana de Reumatologie, 2015, Vol 24, Issue 4, p189
- ISSN
1843-0791
- Publication type
Article
- DOI
10.37897/rjr.2015.4.1