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- Title
Resurgence of respiratory syncytial virus infection during COVID-19 pandemic in Pune, India.
- Authors
Bhardwaj, Sumit; Choudhary, Manohar Lal; Chadha, Mandeep S; Kinikar, Aarti; Bavdekar, Ashish; Gujar, Nilesh; dcosta, Pradeep; Kulkarni, Rajesh; Bafna, Sanjay; Salvi, Sonali; Padbidri, Vikram; Potdar, Varsha
- Abstract
Introduction: Respiratory Syncytial Virus (RSV) is a leading cause of acute lower respiratory infection in children worldwide. Understanding its prevalence, variations, and characteristics is vital, particularly in the context of the COVID-19 pandemic. Objective: The study aimed to investigate the RSV positivity rate, subtype prevalence, age and gender distribution, symptomatology, and co-infection rates during pre-pandemic and pandemic periods. Methods: We analyzed data from 15,381 patients tested for RSV between 2017 and 2023. Results: Our analysis revealed a 7.2% average RSV positivity rate in the pre-pandemic period, with significant fluctuations during the pandemic (1.5% in 2020 to 32.0% in 2021). We observed variations in RSVA and RSVB detection rates. The 0–4 years' age group was consistently the most affected, with a slight male predominance. Fever and cough were common symptoms. Therapeutic interventions, particularly antiviral usage and ventilation requirements, decreased during the pandemic. We also identified variations in co-infection rates with other respiratory viruses. Conclusion: Our study offers critical insights into the impact of the COVID-19 pandemic on RSV prevalence, subtype distribution, patient characteristics, and clinical management. These findings underscore the need for ongoing surveillance and adaptive public health responses.
- Subjects
PUNE (India); RESPIRATORY syncytial virus infections; COVID-19 pandemic; PUBLIC health surveillance; HUMAN metapneumovirus infection; RESPIRATORY infections in children; RESPIRATORY syncytial virus
- Publication
BMC Infectious Diseases, 2024, Issue 1, p1
- ISSN
1471-2334
- Publication type
Article
- DOI
10.1186/s12879-024-09426-6