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- Title
Using intravoxel incoherent motion MR imaging to evaluate cortical defects in the first episode of upper urinary tract infections: Preliminary results.
- Authors
Lee, Chang Hee; Yoo, Kee Hwan; Je, Bo‐Kyung; Kim, In Seong; Kiefer, Berthold; Park, Yang Shin; Kim, Kyeong Ah; Park, Cheol Min
- Abstract
Purpose To compare intravoxel incoherent motion diffusion weight imaging IVIM-DWI MRI with DMSA for the evaluation of cortical defect in pediatric upper urinary tract infection (UTI) patients. Materials and Methods Forty-three kidneys of 22 pediatric patients with the first episode of febrile upper UTI were evaluated. DWI using IVIM model was performed with eight b factors. The presence of cortical defect was evaluated on apparent diffusion coefficient (ADC) map. DMSA was used as the standard of reference. ADC, true diffusion coefficient (D), pseudo-diffusion coefficient (D*), and perfusion fraction (F) in both defect and nondefect area were calculated and compared. Results Cortical defects were detected in 14 kidneys by IVIM-DWI. The sensitivity, specificity, positive predictive value, and negative predictive value of IVIM-DWI MRI for the detection of defects was 93.3%, 100%, 100%, and 96.5%, respectively. Mean values of ADC, D, D*, and F were 1.12 ± 0.15, 1.05 ± 0.10, 33 ± 17 (× 10−3 mm2/s), and 0.14 ± 0.09 in the defect foci. In normal foci, ADC, D, D*, and F were 1.37 ± 0.09, 1.31 ± 0.10, 43 ± 19 (× 10−3 mm2/s), and 0.12 ± 0.04, respectively. ADC and D were significantly lower in defect group than nondefect group ( P < 0.01). Conclusion IVIM-DWI can allow both direct visualization and quantitative measurement of cortical defects. J. Magn. Reson. Imaging 2014;40:545-551. © 2013 Wiley Periodicals, Inc.
- Publication
Journal of Magnetic Resonance Imaging, 2014, Vol 40, Issue 3, p545
- ISSN
1053-1807
- Publication type
Article
- DOI
10.1002/jmri.24384