We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Platinum‐Catalyzed Desaturation of Lactams, Ketones, and Lactones.
- Authors
Chen, Ming; Rago, Alexander J.; Dong, Guangbin
- Abstract
The development of a general platinum‐catalyzed desaturation of N‐protected lactams, ketones, and lactones to their conjugated α,β‐unsaturated counterparts is reported. The reaction operates under mildly acidic conditions at room temperature or 50 °C. It is scalable and tolerates a wide range of functional groups. The complementary reactivity to the palladium‐catalyzed desaturation is demonstrated in the efficient conversion of iodide, bromide, and sulfur‐containing substrates.
- Subjects
PLATINUM; LACTAMS; KETONES; LACTONES; DESATURASES; CATALYSTS
- Publication
Angewandte Chemie, 2018, Vol 130, Issue 49, p16437
- ISSN
0044-8249
- Publication type
Article
- DOI
10.1002/ange.201811197