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- Title
4,5-Seco-Guaiane and a Nine-Membered Sesquiterpene Lactone from Holostylis reniformis.
- Authors
Pereira, Marcos D. P.; Da Silva, Tito; Lopes, Lucia M. X.; Krettli, Antoniana U.; Madureira, Lucas S.; Zukerman-Schpector, Julio
- Abstract
Root extracts of Holostylis reniformis (Aristolochiaceae) yielded three new natural sesquiterpenes, a sesquiterpene with an unusual carbon skeleton, 4,5-seco-guaiane (7-epi-11-hydroxychabrolidione A, 1), a nine-membered lactone with new carbon skeleton (holostylactone, 2), and a new megastigmane [(6S,7E)-6,9-dihydroxy-10-(2'-hydroxyethoxy)- 4,7-megastigmadien-3-one, 3], together with bulnesol and sitosterol-3-O-β-Dglucopyranoside. The structures of these compounds were determined by spectroscopic analyses and B3LYP/STO-3G"" theoretical studies.
- Subjects
ARISTOLOCHIACEAE; SESQUITERPENE lactones; SESQUITERPENES; GLUCOPYRANOSIDE; PLANT extracts
- Publication
Molecules, 2012, Vol 17, Issue 12, p14046
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules171214046