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- Title
Elevated Cardiac Troponin Levels Do Not Predict Adverse Outcomes in Hospitalized Patients without Clinical Manifestations of Acute Coronary Syndromes.
- Authors
Kaushik, Vinod; Barasch, Eddy; Gupta, Richa; Ronen, Pinky; Hartwell, Beth
- Abstract
The prognostic significance of elevated cardiac troponin levels (CTL) in hospitalized patients with no other evidence of myocardial ischemia or injury is largely unknown. Fifty patients (mean age 61 ± 15 years, 15 women) out of 580 consecutive hospitalized patients were selected based on normal CK-MB and at least 3-fold increase of CTL. The medical charts of these patients were reviewed and a 1-year follow-up was performed. The most frequent admission diagnoses were exacerbation of congestive heart failure (22%), stroke (20%) followed by respiratory failure (6%), cirrhosis (6%), gastrointestinal bleeding (6%), end-stage renal disease (4%), atrial fibrillation (4%) and metastatic malignancies (4%). Abnormal CTL prompted a cardiology consult in 48% of patients, an echocardiogram in 44%, myocardial perfusion study in 10% and coronary angiography in 1 patient. Of 21 deaths, only 1 was related to an acute coronary event. The measurement of CTL in patients without definite clinical or electrocardiographic evidence of myocardial ischemia and with a wide spectrum of clinical diagnoses does not predict in-hospital and at 1 year cardiovascular complications and/or cardiac death.Copyright © 2000 S. Karger AG, Basel
- Subjects
PROGNOSIS; CARDIOVASCULAR agents; ECHOCARDIOGRAPHY; MYOCARDIAL reperfusion; CORONARY arterial radiography; EFFECT of drugs on the heart
- Publication
Cardiology, 2000, Vol 93, Issue 1/2, p1
- ISSN
0008-6312
- Publication type
Article