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- Title
The validity of the test of individual equivalence ratios.
- Authors
HWANG, J. T. GENE; WANG, WEIZHEN
- Abstract
We evaluate the validity of the test of individual equivalence ratios (tier), a term coined by Anderson & Hauck (1990). The test was also proposed in Wellek (1989). It is proved to be a valid test under a class of unimodal symmetric distributions; this includes normal distributions. Since most bioequivalence studies involve data which are normal, or at least unimodal and symmetric, the test is typically valid. It is, however, not always valid, as shown by counter examples.
- Subjects
EQUIVALENCE relations (Set theory); TEST validity; SYMMETRIC functions; DISTRIBUTION (Probability theory); MODAL models
- Publication
Biometrika, 1997, Vol 84, Issue 4, p893
- ISSN
0006-3444
- Publication type
Article
- DOI
10.1093/biomet/84.4.893