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- Title
Intramuscular administration of zinc metallothionein to preslaughter-stressed pigs improves anti-oxidative function and pork quality.
- Authors
Li, L. L.; Hou, Z. P.; Liu, Y. H.; Hou, D. X.; Zhang, B.; Wu, G. Y.; Yang, C. B.; Yang, X. J.; Tang, Z. R.; Yin, Y. L.; Fan, M. Z.
- Abstract
This study was conducted to determine the effects of exogenous zinc-metallothionein (Zn-MT) on anti-oxidative function in pork meat. After feeding a corn- and soybean meal-based diet for two weeks, 48 pigs (Duroc×Landrace×Chinese Black Pig) were assigned randomly into one of four treatment groups (12 pigs/group). Pigs in group 1 were maintained under non-stress conditions, whereas pigs in groups 2, 3 and 4 were aggressively handled for 25 min to produce stress. Then, pigs in groups 1 (control group) and 2 (negative control group) received intramuscular administration of saline, while pigs in groups 3 (low dose group) and 4 (high dose group) received 0.8 and 1.6 mg rabbit liver Zn-MT per kg body weight, respectively. Pigs were slaughtered at 3 and 6 h post-injection. Zn-MT treatment increased (P<0.05) the activities of superoxide dismutase (SOD) and glutathione-peroxidase (GSH-PX) while decreasing the concentration of malondialdehyde (MDA) in the liver. These responses were greater (P < 0.05) at 6 h than at 3 h post Zn-MT injection. Zn-MT treatment increased (P < 0.05) hepatic SOD mRNA levels in a time- and dosedependent manner, and decreased (P < 0.05) blood activities of glutamate-pyruvate transaminase and lactate dehydrogenase (indicators of tissue integrity). Zn-MT administration decreased (P < 0.05) lactic acid concentrations, thereby increasing (P < 0.05) the pH and water-holding capacity of the meat. Collectively, our results indicate that intramuscular administration of Zn-MT to preslaughter-stressed pigs improves tissue anti-oxidative ability and pork quality. Supported by funds from the Chinese Academy of Sciences and China NSF.
- Subjects
CHINA; CHINESE Academy of Sciences (Beijing, China); SWINE; PORK; METALLOTHIONEIN; LACTATE dehydrogenase; PYRUVATES; PHYTASES; SUPEROXIDE dismutase; ZINC
- Publication
Journal of Animal Science, 2006, Vol 84, p116
- ISSN
0021-8812
- Publication type
Article