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- Title
Neprilysin Inhibitor May Increase Urinary C-Peptide Excretion.
- Authors
Nishiya, Yuki; Daimon, Makoto; Mizushiri, Satoru; Yanagimachi, Miyuki; Tanabe, Jutaro; Matsuki, Kota; Sato, Eri; Matsumura, Koki
- Abstract
In the article, the authors present a case of 47-year-old woman with diabetes who was rushed to a hospital to improve her glycemic control to discuss how neprilysin inhibitor could increase urinary C-peptide excretion in diabetic patients. Also cited are the use of sacubitril valsartan sodium hydrate or dual angiotensin receptor-neprilysin inhibitor (ARNi) to treat her uncontrolled hypertension, and the use of electrochemiluminescence immunoassay to measure C-peptide concentration.
- Subjects
ANTIHYPERTENSIVE agents; BLOOD pressure; PROTEOLYTIC enzymes; ATRIAL natriuretic peptides; C-peptide; PHARMACODYNAMICS
- Publication
Diabetes Care, 2022, Vol 45, Issue 8, pe122
- ISSN
0149-5992
- Publication type
letter
- DOI
10.2337/dc22-0538