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- Title
苓桂术甘汤对老年脾胃气虚型功能型消化不良患者胃蛋白酶原、胃泌素及血液流变学的影响.
- Authors
林博; 韩冉; 张万宇; 苏金玲; 范金辉
- Abstract
Objective: To study the clinical therapeutic effect of Linggui Zhugan Decoction on elderly patients with functional dyspepsia due to deficiency of spleen and stomach, and to explore the effect of treatment on patients with pepsinogen, gastrin and hemorheology. Methods: A total of 120 elderly patients with functional dyspepsia of spleen-stomach-qi deficiency and functional dyspepsia who were treated in our hospital from January 2020 to October 2021 were selected and divided into a control group and a study group according to the treatment method. The patients in the control group received conventional drug treatment and the patients in the study group In addition to the treatment of patients in the control group, Lingguizhugan Decoction was used for treatment. The clinical treatment efficacy and quality of life score, TCM syndrome score, serum pepsin I and II, serum gastrin-17, and hemorheology were compared between the two groups of patients before and after treatment. Results:(1) The total effective rate of clinical treatment in the study group was significantly higher than that in the control group(93.33 % vs 75.00 %, P<0.05);(2) The quality of life scores of the two groups were significantly increased after treatment, while TCM syndrome scores were reduced, and the improvement of the quality of life scores and TCM syndrome scores of patients in the study group was better than that of the control group(P<0.05);(3) The blood pepsin I and II of the two groups of patients after treatment, Serum gastrin-17 were reduced, and after treatment, the serum pepsin I and II and serum gastrin-17 of the study group were lower than those of the control group(P<0.05);(4) The hemorheology indexes(high-cut whole blood viscosity, low-cut whole blood viscosity and plasma viscosity) of the two groups of patients were reduced after treatment, and the degree of reduction in the study group was significantly higher than that in the control group(P<0.05). Conclusion: The addition of Linggui Zhugan Decoction in the treatment of senile functional dyspepsia of spleen and stomach qi deficiency can significantly improve the clinical therapeutic effect, improve the quality of life of patients, and reduce the expression of serum pepsinogen, gastrin and hemorheology.
- Subjects
BLOOD viscosity; OLDER patients; HEMORHEOLOGY; BLOOD plasma; PEPSINOGEN
- Publication
Progress in Modern Biomedicine, 2022, Vol 22, Issue 10, p1884
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2022.10.018