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- Title
Correlation Expression between P52 and BCL2 among Iraqi Women with Breast Carcinoma.
- Authors
Al-Sudani, Israa Mahdi; Mohammed Ali AlKhafaji, Ali Hussein; Mohammed, Reyadh Salim
- Abstract
Breast cancer is the leading cause of death in women and ranks second in cancer-related mortality in worldwide. NF-𝜅B2(P52) is one of the mammalian NF-κB transcription factor family that expressed in breast tumors. BCL2 is an anti-apoptotic protein that also acts as a medical prognostic biomarker for breast carcinoma. This research was aimed to find out the IHC expression of P52 and BCL2 in 67 histological specimens of breast cancer patients and evaluate their correlation with clinicopathological features. Protein IHC expression of BCL2 and P52 was observed in 45 and 46 respectively. There was no correlation between P52 and BCL2 expression with any clinicopathological parameters, while a strong correlation between protein expression of P52 and BCL2.
- Subjects
BREAST; CARCINOMA; CANCER-related mortality; PROTEIN expression; BREAST cancer; TRANSCRIPTION factors
- Publication
Baghdad Science Journal, 2023, Vol 20, Issue 2, p442
- ISSN
2078-8665
- Publication type
Article
- DOI
10.21123/bsj.2022.7073