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- Title
An Efficient Method for the Preparation of Sulfonamides from Sodium Sulfinates and Amines.
- Authors
Tian, Haiying; Li, Ruiyan; Guo, Fang; Chen, Xiuling
- Abstract
Sulfonamides have a special role on medicine due to their broad biological activities, as bacterial infections, diabetes mellitus, oedema, hypertension prevention and treatment. In addition, sulfonamides are also useful in herbicides and pesticides. Herein, we communicate an efficient strategy for the preparation of sulfonamides via NH4I‐mediated amination of sodium sulfinates. This new method provides a general and environmentally friendly access to sulfonamide compounds and tolerates a wide range of functional groups.
- Subjects
SULFINATES; SULFONAMIDES; SODIUM; AMINES; BACTERIAL diseases
- Publication
ChemistryOpen, 2022, Vol 11, Issue 8, p1
- ISSN
2191-1363
- Publication type
Article
- DOI
10.1002/open.202200097