We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Prediction of pregnancy in infertile women with endometriosis.
- Authors
Murakami, Takashi; Okamura, Chikako; Matsuzaki, Sachiko; Terada, Yukihiro; Yokomizo, Rei; Noda, Takahiro; Yaegashi, Nobuo; Okamura, Kunihiro
- Abstract
To estimate the probability of pregnancy in infertile women with endometriosis, two series of multivariate analyses were performed in Tohoku University Hospital. In the first series, from 1993 to 1997, 103 patients participated. The Cox proportional hazard regression model revealed a hazard ratio of 2.43 in patients with high ovarian adhesion scores. Bilateral ovarian adhesion was an important variable in anatomical factors, probably second only to bilateral tubal adhesion. In the next series, from 1998 to 1999, 23 patients were included, and the preoperative serum concentrations of cytokines, interleukin (IL)-6, IL-8, and tumor necrosis factor (TNF)-alpha were analyzed. Only TNF-alpha was selected with a forward stepwise analysis after forcing age and infertile duration. In the logistic regression model, the serum TNF-alpha level had a significant and negative impact on the likelihood of pregnancy.
- Subjects
DIAGNOSIS of endometriosis; COMPARATIVE studies; CYTOKINES; ENDOMETRIOSIS; INFERTILITY; RESEARCH methodology; MEDICAL cooperation; MULTIVARIATE analysis; PROBABILITY theory; REGRESSION analysis; RESEARCH; LOGISTIC regression analysis; EVALUATION research; PREDICTIVE tests; DISEASE incidence; RETROSPECTIVE studies; SEVERITY of illness index; DISEASE complications; DIAGNOSIS
- Publication
Gynecologic & Obstetric Investigation, 2002, Vol 53, Issue 1, p26
- ISSN
0378-7346
- Publication type
journal article