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- Title
Proteases in host cell invasion by the malaria parasite.
- Authors
Blackman, Michael J.
- Abstract
The life cycle of the malaria parasite contains three distinct invasive forms, or zoites. For at least two of these — the sporozoite and the blood-stage merozoite — invasion into their respective host cell requires the activity of parasite proteases. This review summarizes the evidence for this, discusses selected well-described proteolytic modifications linked to invasion, and describes recent progress towards identifying the proteases involved.
- Subjects
PROTEOLYTIC enzymes; CELLS; MALARIA; PARASITES; FEVER; PROTOZOAN diseases
- Publication
Cellular Microbiology, 2004, Vol 6, Issue 10, p893
- ISSN
1462-5814
- Publication type
Article
- DOI
10.1111/j.1462-5822.2004.00437.x