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- Title
White-matter lesions drive deep gray-matter atrophy in early multiple sclerosis: support from structural MRI.
- Authors
Mühlau, Mark; Buck, Dorothea; Förschler, Annette; Boucard, Christine C; Arsic, Milan; Schmidt, Paul; Gaser, Christian; Berthele, Achim; Hoshi, Muna; Jochim, Angela; Kronsbein, Helena; Zimmer, Claus; Hemmer, Bernhard; Ilg, Rüdiger
- Abstract
The article presents a study on the spatial relationship between lesions of cerebral white matter (WM) and atrophy within deep gray-matter (GM). It mentions the application of a cross-sectional structural magnetic resonance imaging (MRI) analysis in relapsing-remitting multiple sclerosis (RRMS) patients to conduct tow voxel-wise examinations. It also notes the hypothesis of the lesions' contribution to the atrophy through axonal pathology.
- Subjects
WHITE matter (Nerve tissue); PERIAQUEDUCTAL gray matter; MAGNETIC resonance imaging; NERVE tissue; ATROPHY; MULTIPLE sclerosis; HYPOTHESIS; WOUNDS &; injuries
- Publication
Multiple Sclerosis Journal, 2013, Vol 19, Issue 11, p1485
- ISSN
1352-4585
- Publication type
Article
- DOI
10.1177/1352458513478673