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- Title
Impact of guselkumab on three cases of SSc accompanying psoriasis.
- Authors
Fukasawa, Takemichi; Yoshizaki-Ogawa, Asako; Yoshizaki, Ayumi; Sato, Shinichi
- Abstract
The article describes three cases of psoriasis vulgaris (PsV) complicated by systemic sclerosis (SSc) with guselkumab, an interleukin (IL)-23 inhibitor that specifically binds to the IL-23 p19 subunit. Topics include the therapeutic effect of guselkumab on both PsV and SSC, immune abnormalities in SSc, and limitation of the study.
- Subjects
JAPAN; THERAPEUTIC use of monoclonal antibodies; PSORIASIS; DRUG efficacy; BIOPSY; SYSTEMIC scleroderma; INTERSTITIAL lung diseases; MONOCLONAL antibodies; FIBROSIS; GASTROESOPHAGEAL reflux; VASCULAR diseases; COMPUTED tomography; EVALUATION; SYMPTOMS
- Publication
Rheumatology, 2024, Vol 63, Issue 1, pe6
- ISSN
1462-0324
- Publication type
Case Study
- DOI
10.1093/rheumatology/kead287