We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Antioxidant and anticomplement activity of poly[3-(3,4-dihydroxyphenyl)glyceric acid] from Symphytum Asperum and Symphytum Caucasicum plants.
- Authors
Barbakadze, V.; Kemertelidze, E.; Mulkijanyan, K.; Berg, A.; Beukelman, C.; Worm, E.; Quarles van Ufford, H.; Usov, A.
- Abstract
Four water-soluble high-molecular-weight (1000 kDa) fractions isolated from the roots and stems of Symphytum asperum and Symphytum caucasicum plants, in which the principal component is poly[3-3,4-dihydroxyphenyl)glyceric acid], exhibit significant anticomplement and antioxidant activity. These compounds are capable of decreasing the concentration of reactive oxygen species (ROS), either by directly influencing their production by the polymorphonuclear neutrophils or by scavenging these ROS. The high anticomplement and antioxidant properties suggest that this polymer can be a promising basis for antiinflammatory, vasoprotective, and wound-healing drugs.
- Subjects
PLANT-water relationships; ANTIOXIDANTS; COMFREY; PHOTOSYNTHETIC oxygen evolution; REACTIVE oxygen species
- Publication
Pharmaceutical Chemistry Journal, 2007, Vol 41, Issue 1, p14
- ISSN
0091-150X
- Publication type
Article
- DOI
10.1007/s11094-007-0004-7