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- Title
Comparing Safety and Colonization Rates Between Octyl-Isocyanacrylate Glue and Standard Gauze Sponge Dressings for Patients with PICC-PORTs: A Pilot Randomized Controlled Trial.
- Authors
Ntelezos, Konstantinos; Katsoulas, Theodoros; Mariolis-Sapsakos, Theodoros; Galanis, Petros; Alexandrou, Evan; Konstantinou, Evangelos
- Abstract
Introduction: Bacterial colonization in patients with peripherally-inserted implantable ports (PICC-PORTs) is a serious complication that has attributable morbidity and mortality. Methods: We conducted a single center randomized controlled trial comparing safety and effectiveness of octyl-isocyanacrylate glue (GLUE) and standard gauze (SG) dressings for PICC PORT placement. Block randomization was used to allocate patients into the two groups. Swab cultures of the port site were obtained at the end of the procedure and five days after device placement. We assessed the safety of GLUE vs. SG dressings and measured the rate of skin colonization between the two groups. We also estimated the feasibility for conducting a full scale clinical trial. Results: Twenty six patients were randomly allocated to the GLUE group and 25 to the SG dressing group. We observed one case of localized bleeding (GLUE group). We found no cases of localized inflammation or infection at the exit site, no unscheduled dressing changes were reported, and no skin irritation related to either group. There was no difference in the rate of skin colonization post procedure or after five days (p=0.28). Feasibility analysis showed that 98.1% of patients screened were eligible and agreed to enroll in the study and all patients received allocated treatment. Only one patient denied his/her participation in the study. There were no losses to follow up. Conclusions: No difference was found in skin colonization rates between the uses of GLUE or SG dressings for PICC-PORT placement. The high eligibility, recruitment and retention rate show that a larger clinical trial would be feasible.
- Subjects
GREECE; HOST-bacteria relationships; PILOT projects; CULTURES (Biology); FISHER exact test; QUANTITATIVE research; RANDOMIZED controlled trials; PRE-tests &; post-tests; COMPARATIVE studies; T-test (Statistics); DESCRIPTIVE statistics; CHI-squared test; STATISTICAL sampling; DATA analysis software; PATIENT safety; ADHESIVES; SURGICAL dressings
- Publication
International Journal of Caring Sciences, 2022, Vol 15, Issue 2, p1275
- ISSN
1791-5201
- Publication type
Article