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- Title
Bovine Lactoferrin Supplementation for Prevention of Late-Onset Sepsis in Very Low-Birth-Weight Neonates.
- Authors
Manzoni, Paolo; Rinaldi, Matteo; Cattani, Silvia; Pugni, Lorenza; Romeo, Mario Giovanni; Messner, Hubert; Stolfi, Ilaria; Decembrino, Lidia; Laforgia, Nicola; Vagnarelli, Federica; Memo, Luigi; Bordignon, Linda; Saia, Onofrio Sergio; Maule, Milena; Gallo, Elena; Mostert, Michael; Magnani, Cristiana; Quercia, Michele; Bollani, Lina; Pedicino, Roberto
- Abstract
The article discusses a study which investigated the effectiveness of bovine lactoferrin (BLF), alone or in combination with Lactobacillus rhamnosus GG (LGG), to reduce the incidence of late-onset sepsis in very low birth weight (VLBW). The randomized, placebo-controlled trial was conducted in 11 Italian tertiary neonatal intensive care units wherein infants were enrolled from October 1, 2007 through July 31, 2008. The researchers concluded that BLF supplementation was effective in reducing the incidence of late-onset sepsis in VLBW. A comment on the study is presented.
- Subjects
ITALY; LACTOFERRIN; LACTOBACILLUS; LOW birth weight; COMBINED modality therapy; SEPTICEMIA in children; NEONATAL diseases; NEONATAL intensive care; PREVENTION
- Publication
JAMA: Journal of the American Medical Association, 2009, Vol 302, Issue 13, p1421
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/jama.2009.1403