We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Genome Sequence, Comparative Analysis, and Evolutionary Insights into Chitinases of Entomopathogenic Fungus Hirsutella thompsonii.
- Authors
Agrawal, Yamini; Khatri, Indu; Subramanian, Srikrishna; Shenoy, Belle Damodara
- Abstract
Hirsutella thompsonii (Ht) is a fungal pathogen of acarines and the primary cause of epizootics among mites. The draft genomes of two isolates of Ht (MTCC 3556: Ht3, 34.6Mb and MTCC 6686: Ht6, 34.7 Mb) are presented and compared with the genomes of Beauveria bassiana (Bb) ARSEF 2860 and Ophiocordyceps sinensis (Os) CO18. Comparative analysis of carbohydrate active enzymes, Pathogen--host interaction genes, metabolism-associated genes, and genes involved in biosynthesis of secondary metabolites in the four genomes was carried out. Reduction in gene family sizes in Ht3 and Os as compared with Ht6 and Bb is observed. Analysis of the mating type genes in Ht reveals the presence of MAT idiomorphs which is suggestive of cryptic sexual traits in Ht. We further identify and classify putative chitinases that may function as virulence factors in fungal entomopathogens due to their role in degradation of arthropod cuticle.
- Subjects
ENTOMOPATHOGENIC fungi; GENOMES; CHITINASE; GLYCOSIDASES; BIOSYNTHESIS
- Publication
Genome Biology & Evolution, 2015, Vol 7, Issue 3, p916
- ISSN
1759-6653
- Publication type
Article
- DOI
10.1093/gbe/evv037