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Network signatures link hepatic effects of anti-diabetic interventions with systemic disease parameters.
Published in:
BMC Systems Biology, 2014, v. 8, n. 1, p. 1, doi. 10.1186/s12918-014-0108-0
By:
- Kelder, Thomas;
- Verschuren, Lars;
- van Ommen, Ben;
- van Gool, Alain J.;
- Radonjic, Marijana
Publication type:
Article
Systems biology of personalized nutrition.
Published in:
Nutrition Reviews, 2017, v. 75, n. 8, p. 579, doi. 10.1093/nutrit/nux029
By:
- van Ommen, Ben;
- van den Broek, Tim;
- de Hoogh, Iris;
- van Erk, Marjan;
- van Someren, Eugene;
- Rouhani-Rankouhi, Tanja;
- Hogenelst, Koen;
- Pasman, Wilrike;
- Boorsma, André;
- Wopereis, Suzan;
- Anthony, Joshua C.
Publication type:
Article
The Metabolomics Standards Initiative.
Published in:
2007
By:
- Sansone, Susanna-Assunta;
- Fan, Teresa;
- Goodacre, Royston;
- Griffin, Julian L;
- Hardy, Nigel W;
- Kaddurah-Daouk, Rima;
- Kristal, Bruce S;
- Lindon, John;
- Mendes, Pedro;
- Morrison, Norman;
- Nikolau, Basil;
- Robertson, Don;
- Sumner, Lloyd W;
- Taylor, Chris;
- van der Werf, Mariët;
- van Ommen, Ben;
- Fiehn, Oliver
Publication type:
Letter
Developing computational model-based diagnostics to analyse clinical chemistry data.
Published in:
Briefings in Bioinformatics, 2010, v. 11, n. 4, p. 403, doi. 10.1093/bib/bbp071
By:
- Van Schalkwijk, Daniël B.;
- Van Bochove, Kees;
- Van Ommen, Ben;
- Freidig, Andreas P.;
- Van Someren, Eugene P.;
- Van der Greef, Jan;
- De Graaf, Albert A.
Publication type:
Article
Lipoprotein Metabolism Indicators Improve Cardiovascular Risk Prediction.
Published in:
PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0092840
By:
- van Schalkwijk, Daniël B.;
- de Graaf, Albert A.;
- Tsivtsivadze, Evgeni;
- Parnell, Laurence D.;
- van der Werff-van der Vat, Bianca J. C.;
- van Ommen, Ben;
- van der Greef, Jan;
- Ordovás, José M.
Publication type:
Article
Differential Effects of Drug Interventions and Dietary Lifestyle in Developing Type 2 Diabetes and Complications: A Systems Biology Analysis in LDLr−/− Mice.
Published in:
PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056122
By:
- Radonjic, Marijana;
- Wielinga, Peter Y.;
- Wopereis, Suzan;
- Kelder, Thomas;
- Goelela, Varshna S.;
- Verschuren, Lars;
- Toet, Karin;
- van Duyvenvoorde, Wim;
- van der Werff van der Vat, Bianca;
- Stroeve, Johanna H. M.;
- Cnubben, Nicole;
- Kooistra, Teake;
- van Ommen, Ben;
- Kleemann, Robert
Publication type:
Article
Clustering by Plasma Lipoprotein Profile Reveals Two Distinct Subgroups with Positive Lipid Response to Fenofibrate Therapy.
Published in:
PLoS ONE, 2012, v. 7, n. 6, p. e38072, doi. 10.1371/journal.pone.0038072
By:
- van Bochove, Kees;
- van Schalkwijk, Daniël B.;
- Parnell, Laurence D.;
- Chao-Qiang Lai;
- Ordovás, José M.;
- de Graaf, Albert A.;
- van Ommen, Ben;
- Arnett, Donna K.
Publication type:
Article
Time-Resolved and Tissue-Specific Systems Analysis of the Pathogenesis of Insulin Resistance.
Published in:
PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008817
By:
- Kleemann, Robert;
- van Erk, Marjan;
- Verschuren, Lars;
- van den Hoek, Anita M.;
- Koek, Maud;
- Wielinga, Peter Y.;
- Jie, Annie;
- Pellis, Linette;
- Bobeldijk-Pastorova, Ivana;
- Kelder, Thomas;
- Toet, Karin;
- Wopereis, Suzan;
- Cnubben, Nicole;
- Evelo, Chris;
- van Ommen, Ben;
- Kooistra, Teake
Publication type:
Article
Genome-Wide mRNA Expression Analysis of Hepatic Adaptation to High-Fat Diets Reveals Switch from an Inflammatory to Steatotic Transcriptional Program.
Published in:
PLoS ONE, 2009, v. 4, n. 8, p. 1, doi. 10.1371/journal.pone.0006646
By:
- Radonjic, Marijana;
- de Haan, Jorn R.;
- van Erk, Marjan J.;
- van Dijk, Ko Willems;
- van den Berg, Sjoerd A. A.;
- de Groot, Philip J.;
- Müller, Michael;
- van Ommen, Ben
Publication type:
Article
Metabolic Profiling of the Response to an Oral Glucose Tolerance Test Detects Subtle Metabolic Changes.
Published in:
PLoS ONE, 2009, v. 4, n. 2, p. 1, doi. 10.1371/journal.pone.0004525
By:
- Wopereis, Suzan;
- Rubingh, Carina M.;
- van Erk, Marjan J.;
- Verheij, Elwin R.;
- van Vliet, Trinette;
- Cnubben, Nicole H. P.;
- Smilde, Age K.;
- van der Greef, Jan;
- van Ommen, Ben;
- Hendriks, Henk F. J.
Publication type:
Article
Proposed guidelines to evaluate scientific validity and evidence for genotype-based dietary advice.
Published in:
Genes & Nutrition, 2017, v. 12, p. 1, doi. 10.1186/s12263-017-0584-0
By:
- Grimaldi, Keith A.;
- van Ommen, Ben;
- Ordovas, Jose M.;
- Parnell, Laurence D.;
- Mathers, John C.;
- Bendik, Igor;
- Brennan, Lorraine;
- Celis-Morales, Carlos;
- Cirillo, Elisa;
- Daniel, Hannelore;
- de Kok, Brenda;
- El-Sohemy, Ahmed;
- Fairweather-Tait, Susan J.;
- Fallaize, Rosalind;
- Fenech, Michael;
- Ferguson, Lynnette R.;
- Gibney, Eileen R.;
- Gibney, Mike;
- Gjelstad, Ingrid M. F.;
- Kaput, Jim
Publication type:
Article
Multi-parameter comparison of a standardized mixed meal tolerance test in healthy and type 2 diabetic subjects: the PhenFlex challenge.
Published in:
Genes & Nutrition, 2017, v. 12, p. 1, doi. 10.1186/s12263-017-0570-6
By:
- Wopereis, Suzan;
- Stroeve, Johanna H. M.;
- Stafleu, Annette;
- Bakker, Gertruud C. M.;
- Burggraaf, Jacobus;
- van Erk, Marjan J.;
- Pellis, Linette;
- Boessen, Ruud;
- Kardinaal, Alwine A. F.;
- van Ommen, Ben
Publication type:
Article
The impact of micronutrient status on health: correlation network analysis to understand the role of micronutrients in metabolic-inflammatory processes regulating homeostasis and phenotypic flexibility.
Published in:
Genes & Nutrition, 2017, v. 12, n. 5, p. 1, doi. 10.1186/s12263-017-0553-7
By:
- van den Broek, Tim J.;
- Kremer, Bas H. A.;
- Rezende, Marisa Marcondes;
- Hoevenaars, Femke P. M.;
- Weber, Peter;
- Hoeller, Ulrich;
- van Ommen, Ben;
- Wopereis, Suzan
Publication type:
Article
Phenotypic flexibility as a measure of health: the optimal nutritional stress response test.
Published in:
Genes & Nutrition, 2015, v. 10, n. 3, p. 1, doi. 10.1007/s12263-015-0459-1
By:
- Stroeve, Johanna H. M.;
- van Wietmarschen, Herman;
- Kremer, Bas H. A.;
- van Ommen, Ben;
- Wopereis, Suzan
Publication type:
Article
Personalized nutrition from a health perspective: luxury or necessity?
Published in:
Genes & Nutrition, 2007, v. 2, n. 1, p. 3, doi. 10.1007/s12263-007-0018-5
By:
- van Ommen, Ben
Publication type:
Article
Metabolomics of prolonged fasting in humans reveals new catabolic markers.
Published in:
Metabolomics, 2011, v. 7, n. 3, p. 375, doi. 10.1007/s11306-010-0255-2
By:
- Rubio-Aliaga, Isabel;
- de Roos, Baukje;
- Duthie, Susan J.;
- Crosley, L.;
- Mayer, Claus;
- Horgan, Graham;
- Colquhoun, Ian J.;
- Le Gall, Gwénaëlle;
- Huber, Fritz;
- Kremer, Werner;
- Rychlik, Michael;
- Wopereis, Suzan;
- van Ommen, Ben;
- Schmidt, Gabriele;
- Heim, Carolin;
- Bouwman, Freek G.;
- Mariman, Edwin C.;
- Mulholland, Francis;
- Johnson, Ian T.;
- Polley, Abigael C.
Publication type:
Article
Filling gaps in PPAR-alpha signaling through comparativenutrigenomics analysis.
Published in:
BMC Genomics, 2009, v. 10, p. 596, doi. 10.1186/1471-2164-10-596
By:
- Cavalieri, Duccio;
- Calura, Enrica;
- Romualdi, Chiara;
- Marchi, Emmanuela;
- Radonjic, Marijana;
- Van Ommen, Ben;
- Müller, Michael
Publication type:
Article
Improving the analysis of designed studies by combining statistical modelling with study design information.
Published in:
BMC Bioinformatics, 2009, v. 10, p. 1, doi. 10.1186/1471-2105-10-52
By:
- Thissen, Uwe;
- Wopereis, Suzan;
- van den Berg, Sjoerd A. A.;
- Bobeldijk, Ivana;
- Kleemann, Robert;
- Kooistra, Teake;
- van Dijk, Ko Willems;
- van Ommen, Ben;
- Smilde, Age K.
Publication type:
Article
The role of cyclooxygenase in n-6 and n-3 polyunsaturated fatty acid mediated effects on cell proliferation, PGE2 synthesis and cytotoxicity in human colorectal carcinoma cell lines.
Published in:
Carcinogenesis, 2003, v. 24, n. 3, p. 385, doi. 10.1093/carcin/24.3.385
By:
- Dommels, Yvonne E.M.;
- Haring, Merel M.G.;
- Keestra, Nynke G.M.;
- Alink, Gerrit M.;
- van Bladeren, Peter J.;
- van Ommen, Ben
Publication type:
Article
Integrated assessment by multiple gene expression analysis of quercetin bioactivity on anticancer-related mechanisms in colon cancer cells in vitro.
Published in:
European Journal of Nutrition, 2005, v. 44, n. 3, p. 143, doi. 10.1007/s00394-004-0503-1
By:
- Erk, Marjan J.;
- Roepman, Paul;
- van der Lende, Ted R.;
- Stierum, Rob H.;
- Aarts, Jac M. M. J. G.;
- van Bladeren, Peter J.;
- van Ommen, Ben
Publication type:
Article
A systems biology approach to understand the pathophysiological mechanisms of cardiac pathological hypertrophy associated with rosiglitazone.
Published in:
BMC Medical Genomics, 2014, v. 7, n. 1, p. 2, doi. 10.1186/1755-8794-7-35
By:
- Verschuren, Lars;
- Wielinga, Peter Y.;
- Kelder, Thomas;
- Radonjic, Marijana;
- Salic, Kanita;
- Kleemann, Robert;
- van Ommen, Ben;
- Kooistra, Teake
Publication type:
Article
Assessment of inflammatory resilience in healthy subjects using dietary lipid and glucose challenges.
Published in:
BMC Medical Genomics, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1755-8794-6-44
By:
- Wopereis, Suzan;
- Wolvers, Danielle;
- van Erk, Marjan;
- Gribnau, Michiel;
- Kremer, Bas;
- van Dorsten, Ferdi A.;
- Boelsma, Esther;
- Garczarek, Ursula;
- Cnubben, Nicole;
- Frenken, Leon;
- van der Logt, Paul;
- Hendriks, Henk F. J.;
- Albers, Ruud;
- van Duynhoven, John;
- van Ommen, Ben;
- Jacobs, Doris M.
Publication type:
Article
Visualization and identification of health space, based on personalized molecular phenotype and treatment response to relevant underlying biological processes.
Published in:
BMC Medical Genomics, 2012, v. 5, n. 1, p. 1, doi. 10.1186/1755-8794-5-1
By:
- Bouwman, Jildau;
- Vogels, Jack T. W. E.;
- Wopereis, Suzan;
- Rubingh, Carina M.;
- Bijlsma, Sabina;
- van Ommen, Ben
Publication type:
Article
Insight in modulation of inflammation in response to diclofenac intervention: a human intervention study.
Published in:
BMC Medical Genomics, 2010, v. 3, p. 5, doi. 10.1186/1755-8794-3-5
By:
- van Erk, Marjan J.;
- Wopereis, Suzan;
- Rubingh, Carina;
- van Vliet, Trinette;
- Verheij, Elwin;
- Cnubben, Nicole H. P.;
- Pedersen, Theresa L.;
- Newman, John W.;
- Smilde, Age K.;
- van der Greef, Jan;
- Hendriks, Henk F. J.;
- van Ommen, Ben
Publication type:
Article
Plasma metabolome analysis identifies distinct human metabotypes in the postprandial state with different susceptibility to weight loss-mediated metabolic improvements.
Published in:
FASEB Journal, 2018, v. 32, n. 10, p. 5447, doi. 10.1096/fj.201800330R
By:
- Fiamoncini, Jarlei;
- Rundle, Milena;
- Gibbons, Helena;
- Thomas, E. Louise;
- Geillinger-Kästle, Kerstin;
- Bunzel, Diana;
- Trezzi, Jean-Pierre;
- Kiselova-Kaneva, Yoana;
- Wopereis, Suzan;
- Wahrheit, Judith;
- Kulling, Sabine E.;
- Hiller, Karsten;
- Sonntag, Denise;
- Ivanova, Diana;
- van Ommen, Ben;
- Frost, Gary;
- Brennan, Lorraine;
- Bell, Jimmy;
- Daniel, Hannelore
Publication type:
Article
Quantifying phenotypic flexibility as the response to a high-fat challenge test in different states of metabolic health.
Published in:
FASEB Journal, 2015, v. 29, n. 11, p. 4600, doi. 10.1096/fj.14-269852
By:
- Kardinaal, Alwine F. M.;
- van Erk, Marjan J.;
- Dutman, Alice E.;
- Stroeve, Johanna H. M.;
- van de Steeg, Evita;
- Bijlsma, Sabina;
- Kooistra, Teake;
- van Ommen, Ben;
- Wopereis, Suzan
Publication type:
Article
Holistic multilevel modeling of type‐2 diabetes (1180.5).
Published in:
FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.1180.5
By:
- de Graaf, Albert;
- van Ommen, Ben
Publication type:
Article
Transcriptomic Coordination in the Human Metabolic Network Reveals Links between n-3 Fat Intake, Adipose Tissue Gene Expression and Metabolic Health.
Published in:
PLoS Computational Biology, 2011, v. 7, n. 11, p. 1, doi. 10.1371/journal.pcbi.1002223
By:
- Morine, Melissa J.;
- Tierney, Audrey C.;
- van Ommen, Ben;
- Daniel, Hannelore;
- Toomey, Sinead;
- Gjelstad, Ingrid M. F.;
- Gormley, Isobel C.;
- Pérez-Martinez, Pablo;
- Drevon, Christian A.;
- López-Miranda, Jose;
- Roche, Helen M.
Publication type:
Article
Nutritional Systems Biology Modeling: From Molecular Mechanisms to Physiology.
Published in:
PLoS Computational Biology, 2009, v. 5, n. 11, p. 1, doi. 10.1371/journal.pcbi.1000554
By:
- de Graaf, Albert A.;
- Freidig, Andreas P.;
- de Roos, Baukje;
- Jamshidi, Neema;
- Heinemann, Matthias;
- Rullmann, Johan A. C.;
- Hall, Kevin D.;
- Adiels, Martin;
- van Ommen, Ben
Publication type:
Article
Nutrigenomics: The Impact of Biomics Technology on Nutrition Research.
Published in:
Annals of Nutrition & Metabolism, 2005, v. 49, n. 6, p. 355, doi. 10.1159/000088315
By:
- Corthésy-Theulaz, Irène;
- Den Dunnen, Johan T.;
- Ferré, Pascal;
- Geurts, Jan M. W.;
- Müller, Michael;
- Van Belzen, Nico;
- Van Ommen, Ben
Publication type:
Article
Challenging homeostasis to define biomarkers for nutrition related health.
Published in:
Molecular Nutrition & Food Research, 2009, v. 53, n. 7, p. 795, doi. 10.1002/mnfr.200800390
By:
- van Ommen, Ben;
- Keijer, Jaap;
- Heil, Sandra G.;
- Kaput, Jim
Publication type:
Article
Time- and dose-dependent effects of curcumin on gene expression in human colon cancer cells.
Published in:
Journal of Carcinogenesis, 2004, v. 3, n. 1, p. 8, doi. 10.1186/1477-3163-3-8
By:
- Van Erk, Marjan J.;
- Teuling, Eva;
- Staal, Yvonne C. M.;
- Huybers, Sylvie;
- Van Bladeren, Peter J.;
- Aarts, Jac M. M. J. G.;
- Van Ommen, Ben
Publication type:
Article
Bromobenzene-Induced Hepatotoxicity at the Transcriptome Level.
Published in:
Toxicological Sciences, 2004, v. 79, n. 2, p. 411, doi. 10.1093/toxsci/kfh128
By:
- Heijne, Wilbert H. M.;
- Slitt, Angela L.;
- van Bladeren, Peter J.;
- Groten, John P.;
- Klaassen, Curtis D.;
- Stierum, Rob H.;
- van Ommen, Ben
Publication type:
Article
From Diabetes Care to Diabetes Cure--The Integration of Systems Biology, eHealth, and Behavioral Change.
Published in:
Frontiers in Endocrinology, 2018, p. 1, doi. 10.3389/fendo.2017.00381
By:
- van Ommen, Ben;
- Wopereis, Suzan;
- van Empelen, Pepijn;
- van Keulen, Hilde M.;
- Otten, Wilma;
- Kasteleyn, Marise;
- Molema, Johanna J. W.;
- de Hoogh, Iris M.;
- Chavannes, Niels H.;
- Numans, Mattijs E.;
- Evers, Andrea W. M.;
- Pijl, Hanno
Publication type:
Article
Looking back into the future: 30 years of metabolomics at TNO.
Published in:
Mass Spectrometry Reviews, 2013, v. 32, n. 5, p. 399, doi. 10.1002/mas.21370
By:
- van der Greef, Jan;
- van Wietmarschen, Herman;
- van Ommen, Ben;
- Verheij, Elwin
Publication type:
Article
Effects of a 13-Week Personalized Lifestyle Intervention Based on the Diabetes Subtype for People with Newly Diagnosed Type 2 Diabetes.
Published in:
Biomedicines, 2022, v. 10, n. 3, p. 643, doi. 10.3390/biomedicines10030643
By:
- de Hoogh, Iris M.;
- Pasman, Wilrike J.;
- Boorsma, André;
- van Ommen, Ben;
- Wopereis, Suzan
Publication type:
Article
A plasma circulating miRNAs profile predicts type 2 diabetes mellitus and prediabetes: from the CORDIOPREV study.
Published in:
Experimental & Molecular Medicine EMM, 2018, v. 50, n. 12, p. 1, doi. 10.1038/s12276-018-0194-y
By:
- Jiménez-Lucena, Rosa;
- Camargo, Antonio;
- Alcalá-Diaz, Juan Francisco;
- Romero-Baldonado, Cristina;
- Luque, Raúl Miguel;
- van Ommen, Ben;
- Delgado-Lista, Javier;
- Ordovás, Jose María;
- Pérez-Martínez, Pablo;
- Rangel-Zúñiga, Oriol Alberto;
- López-Miranda, Jose
Publication type:
Article
Profiles of Metabolites and Gene Expression in Rats with Chemically Induced Hepatic Necrosis.
Published in:
Toxicologic Pathology, 2005, v. 33, n. 4, p. 425, doi. 10.1080/01926230590958146
By:
- Heijne, Wilbert H. M.;
- Lamers, Robert-Jan A. N.;
- Van Bladeren, Peter J.;
- Groten, John P.;
- Van Nesselrooij, Joop H. J.;
- Van Ommen, Ben
Publication type:
Article
Weight loss predictability by plasma metabolic signatures in adults with obesity and morbid obesity of the DiOGenes study.
Published in:
2016
By:
- Stroeve, Johanna H.M.;
- Saccenti, Edoardo;
- Bouwman, Jildau;
- Dane, Adrie;
- Strassburg, Katrin;
- Vervoort, Jacques;
- Hankemeier, Thomas;
- Astrup, Arne;
- Smilde, Age K.;
- van Ommen, Ben;
- Saris, Wim H.M.
Publication type:
journal article
Personalized lifestyle to prevent, revert and remit type 2 diabetes in primary care practice.
Published in:
Nederlands Tijdschrift voor Diabetologie (NTvD), 2023, v. 21, n. 4, p. 56
By:
- Wopereis, Suzan;
- de Hoogh, Iris M.;
- Oosterman, Johanneke E.;
- Smid, Dagmar;
- Kamstra, Regina J. M.;
- Otten, Wilma;
- Krijger, Anne-Margreeth;
- Berbée-Zadelaar, Susanne;
- Pijl, Hanno;
- Boorsma, Andre;
- van Ommen, Ben;
- Pasman, Wilrike J.
Publication type:
Article
The Effect of a Lifestyle Intervention on Type 2 Diabetes Pathophysiology and Remission: The Stevenshof Pilot Study.
Published in:
Nutrients, 2021, v. 13, n. 7, p. 2193, doi. 10.3390/nu13072193
By:
- de Hoogh, Iris M.;
- Oosterman, Johanneke E.;
- Otten, Wilma;
- Krijger, Anne-Margreeth;
- Berbée-Zadelaar, Susanne;
- Pasman, Wilrike J.;
- van Ommen, Ben;
- Pijl, Hanno;
- Wopereis, Suzan
Publication type:
Article
Mediterranean Diet Adherence and Genetic Background Roles within a Web-Based Nutritional Intervention: The Food4Me Study.
Published in:
Nutrients, 2017, v. 9, n. 10, p. 1107, doi. 10.3390/nu9101107
By:
- San-Cristobal, Rodrigo;
- Navas-Carretero, Santiago;
- Martinez, J. Alfredo;
- Drevon, Christian A.;
- Gundersen, Thomas E.;
- Grimaldi, Keith;
- Parnell, Laurence D.;
- Bouwman, Jildau;
- Van Ommen, Ben;
- Livingstone, Katherine M.;
- Celis-Morales, Carlos;
- Mathers, John C.;
- Macready, Anna L.;
- Fallaize, Rosalind;
- Lovegrove, Julie A.;
- O'Donovan, Clare B.;
- Gibney, Eileen R.;
- Brennan, Lorraine;
- Gibney, Mike;
- Lambrinou, Christina P.
Publication type:
Article

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