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- Title
Mycobacterium chimaera Infections Related to the Heater–Cooler Unit Outbreak: A Guide to Diagnosis and Management.
- Authors
Kasperbauer, Shannon H; Daley, Charles L
- Abstract
We are in the midst of a global outbreak of Mycobacterium chimaera infections related to a point source contamination of a widely used surgical device, the 3T heater–cooler unit. More than 250000 heart bypass procedures using heater–cooler devices are performed in the United States every year. It is estimated that 60% of these operations use the device associated with this outbreak. Most of the reported cases present with a disseminated infection that is striking in both the latency of presentation and the high mortality. The diagnosis can be elusive due to intermittent bacteremia and normal echocardiography. Therapy includes several months of antibiotics, and surgical intervention appears to be critical for successful outcomes. Here, we review diagnostic methods and treatment options to guide clinicians in the management of this complicated infection.
- Subjects
UNITED States; ANTIBIOTICS; HEATING equipment; MYCOBACTERIAL disease diagnosis; MYCOBACTERIAL disease treatment; ATTITUDE (Psychology); ECHOCARDIOGRAPHY; DISEASE outbreaks; MEDICAL personnel; MEDICAL protocols; MYCOBACTERIAL diseases; DISEASE management; TREATMENT effectiveness; MEDICAL equipment contamination
- Publication
Clinical Infectious Diseases, 2019, Vol 68, Issue 7, p1244
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciy789