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- Title
N-acyl Homoserine Lactone-Producing Pseudomonas putida Strain T2-2 from Human Tongue Surface.
- Authors
Jian-Woon Chen; Shenyang Chin; Kok Keng Tee; Wai-Fong Yin; Yeun Mun Choo; Kok-Gan Chan
- Abstract
Bacterial cell-to-cell communication (quorum sensing) refers to the regulation of bacterial gene expression in response to changes in microbial population density. Quorum sensing bacteria produce, release and respond to chemical signal molecules called autoinducers. Bacteria use two types of autoinducers, namely autoinducer-1 (AI-1) and autoinducer-2 (AI-2) where the former are N-acylhomoserine lactones and the latter is a product of the luxS gene. Most of the reported literatures show that the majority of oral bacteria use AI-2 for quorum sensing but rarely the AI-1 system. Here we report the isolation of Pseudomonas putida strain T2-2 from the oral cavity. Using high resolution mass spectrometry, it is shown that this isolate produced N-octanoylhomoserine lactone (C8-HSL) and N-dodecanoylhomoserine lactone (C12-HSL) molecules. This is the first report of the finding of quorum sensing of P. putida strain T2-2 isolated from the human tongue surface and their quorum sensing molecules were identified.
- Subjects
QUORUM sensing; BACTERIAL genetics; GENE expression; MOLECULAR genetics; MICROORGANISM populations
- Publication
Sensors (14248220), 2013, Vol 13, Issue 10, p13192
- ISSN
1424-8220
- Publication type
Article
- DOI
10.3390/s131013192