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- Title
Fine needle aspiration cytology: An in vitro study of cell yield.
- Authors
Hartley, M. N.; Tuffnell, D. J.; Hutton, Jane L.; Palmer, Margaret; Al-Jafari, M. S.
- Abstract
To investigate the effect of needle size and number of passes into a tumour mass on the cell yield from a fine needle aspirate, an in vitro study was undertaken in 19 consecutive tumours removed surgically for biopsy. Different needle sizes (23G, 21G, 19G) passed in random order, five, ten and fifteen times into the tumours, were compared. The type of tumour, needle size and number of passes independently and significantly influenced cell yield. A 21G(green) needle passed into the tumour at least 10 times was the most efficient in obtaining cells. This in vitro study could explain the variation in the reported accuracy of fine needle aspiration cytology from groups using different techniques and is perhaps one reason why the highest diagnostic accuracy and the lowest rate of unsatisfactory aspirates comes from a centre which uses a 21G needle and at least 10 passes through the tumour.
- Publication
British Journal of Surgery, 1988, Vol 75, Issue 4, p380
- ISSN
0007-1323
- Publication type
Article
- DOI
10.1002/bjs.1800750428