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- Title
The Role of Citicoline and Coenzyme Q10 in Retinal Pathology.
- Authors
García-López, Claudia; García-López, Verónica; Matamoros, José A.; Fernández-Albarral, José A.; Salobrar-García, Elena; de Hoz, Rosa; López-Cuenca, Inés; Sánchez-Puebla, Lidia; Ramírez, José M.; Ramírez, Ana I.; Salazar, Juan J.
- Abstract
Ocular neurodegenerative diseases such as glaucoma, diabetic retinopathy, and age-related macular degeneration are common retinal diseases responsible for most of the blindness causes in the working-age and elderly populations in developed countries. Many of the current treatments used in these pathologies fail to stop or slow the progression of the disease. Therefore, other types of treatments with neuroprotective characteristics may be necessary to allow a more satisfactory management of the disease. Citicoline and coenzyme Q10 are molecules that have neuroprotective, antioxidant, and anti-inflammatory properties, and their use could have a beneficial effect in ocular neurodegenerative pathologies. This review provides a compilation, mainly from the last 10 years, of the main studies that have been published on the use of these drugs in these neurodegenerative diseases of the retina, analyzing the usefulness of these drugs in these pathologies.
- Subjects
CYTIDINE diphosphate choline; MACULAR degeneration; RETINAL diseases; PATHOLOGY; UBIQUINONES; DIABETIC retinopathy
- Publication
International Journal of Molecular Sciences, 2023, Vol 24, Issue 6, p5072
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms24065072