We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
THE RAT AMELOGENIN GENE -- SOME ASPECTS OF EVOLUTION AND EXPRESSION.
- Authors
BONASS, W. A.; BROOKES, S. J.; KIRKHAM, J.; SHORE, R. C.; ROBINSON, C.
- Abstract
This study presents data to support the hypothesis that a major portion of the coding sequence of the amelogenin gene may have arisen by tandem duplication of internal sequences which as a consequence has introduced several additional potential RNA splice acceptor sites into the sequence. This duplication of splice sites has led to an increase in the heterogeneity of amelogenin forms found in developing enamel. By screening a rat enamel organ cDNA library for alternatively spliced products, it appears that as much as 20% of the amelogenin mRNA molecules may be alternatively spliced forms.
- Subjects
AMELOGENIN; GENES; GENE expression; LABORATORY rats; RNA; DENTAL enamel
- Publication
Advances in Dental Research, 1996, Vol 10, Issue 2, p182
- ISSN
0895-9374
- Publication type
Article
- DOI
10.1177/08959374960100021101