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- Title
A case of DRESS (drug reaction with eosinophilia and systemic symptoms) with acute interstitial nephritis secondary to lenalidomide.
- Authors
Shaaban, Hamid; Layne, Trevor; Guron, Gunwant
- Abstract
Acute kidney injury is commonly observed in patients with multiple myeloma and other plasma cell dyscrasias. The pathophysiologic causes, however, are varied. We report a case of a severe ‘drug reaction with eosinophilia and systemic symptoms’ syndrome associated with acute interstitial nephritis in a patient with multiple myeloma likely related to the administration of lenalidomide. This disease entity requires prompt recognition and cessation of the offending drug and often treatment with high-dose corticosteroids.
- Subjects
DRUG allergy; EOSINOPHILIA; IMMUNOLOGICAL adjuvants; MULTIPLE myeloma; INTERSTITIAL nephritis; SYNDROMES; ACUTE diseases
- Publication
Journal of Oncology Pharmacy Practice, 2014, Vol 20, Issue 4, p302
- ISSN
1078-1552
- Publication type
Article
- DOI
10.1177/1078155213502569