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- Title
A Retrospective Review of Long-term Ovarian Cancer Survivors and their Use of Hormone Therapy versus no Hormone Therapy.
- Authors
Mitchell, S. K.; Carson, L. F.; Biegert, D. J.; Schempp, A. L.; Downs, L. S.
- Abstract
We conducted a retrospective review of thirty ovarian cancer patients whose initial date of diagnosis was from 1903 to 1999 and compared the use of estrogen versus no estrogen use after cancer treatment. We also compared age at diagnosis, stage, response to therapy and survival. Eleven patients received estrogen, all at equivalent doses. Their average age 54.4 years and the stage of disease was, Stage I (2) Stage 2 (1) Stage 3 (7) Stags 4 (1). Three patients had persistent disease, 1 recurrent, and 7 with no evidence of disease, average survival of 7.8 years. Nineteen patients receiving no estrogen, their average age was 53.7 years and stage of disease was Stage I (2) Stage 2 (I) Stage 3 (11) Stage 4 (4) Unstaged (1). 4 patients had persistent disease, i1 recurred, 4 with no evidence of disease, average survival 8.05 years. It should be noted that all patients in both groups are alive to date. T-test was conducted to compare the age and years of follow-up between patients receiving and not receiving estrogen using chi-square test. In this study women who received estrogen were more likely to be NED than women who did not receive estrogen (p=0.05). There were no detectable differences between women with recurrent versus persistent disease (p=0.12). The current prescribing of estrogen is very controversial, m our small cohort of patients there does not appear to be any detrimental effects. Further research in this area is needed.
- Subjects
OVARIAN cancer; CANCER patients; ESTROGEN; CANCER treatment; T-test (Statistics)
- Publication
Journal of Gynecologic Oncology Nursing, 2005, Vol 15, Issue 3, p18
- ISSN
1536-9935
- Publication type
Article