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- Title
Plasma free amino acid profiles of canine mammary gland tumors.
- Authors
Azuma, Kazuo; Osaki, Tomohiro; Tsuka, Takeshi; Imagawa, Tomohiro; Minami, Saburo; Okamoto, Yoshiharu
- Abstract
The purpose of this study was to elucidate the relationship between plasma free amino acid (PFAA) levels and the clinical stages of mammary gland tumors (MGT) in dogs. PFAA levels in canines with malignant mammary tumors were decreased compared to those of healthy animals. The levels of aspartate and ornithine, in the dogs with tumor metastasis were significantly decreased when compared to those of dogs that did not have metastases. Results of this study indicate that PFAA levels could be a risk factor or biomarker for canine MGT metastasis.
- Subjects
MAMMARY gland tumors; AMINO acids; BIOMARKERS; METASTASIS; BLOOD plasma; ORNITHINE; ASPARTIC acid; DOG diseases
- Publication
Journal of Veterinary Science, 2012, Vol 13, Issue 4, p433
- ISSN
1229-845X
- Publication type
Article
- DOI
10.4142/jvs.2012.13.4.433