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- Title
Bilateral Atypical Femur Fractures After Denosumab in a Bisphosphonate Naive Patient: A Case Report.
- Authors
Goh, Jeremy Keng Meng; Koh, Joyce Suang Bee; Ng, Alvin Choong Meng; Png, Meng Ai; Howe, Tet Sen
- Abstract
A case report of bilateral atypical femur fractures (AFF) in a bisphosphonate naive patient. A 62-year-old female bisphosphonate naive patient was started on denosumab for osteoporosis. Approximately 3 years later she complained of right hip pain and was found to have a bilateral incomplete AFFs. She was asymptomatic on the left lower limb. Patient was managed conservatively and placed on protected weight bearing on both legs. Symptoms subsequently resolved over a period of 3 months, although radiographic findings remained at approximately 1 year. AFFs may be associated with patients on denosumab therapy even without a prior history of bisphosphonate use. Patients should be counselled appropriately and monitored for such complications.
- Subjects
FEMORAL fractures; DENOSUMAB; FEMUR; STRESS fractures (Orthopedics)
- Publication
Calcified Tissue International, 2022, Vol 111, Issue 1, p96
- ISSN
0171-967X
- Publication type
Article
- DOI
10.1007/s00223-022-00952-6